C₂₀H₂₂O₂

Base Information

• Chemical Name: C₂₀H₂₂O₂
• CAS No.: 1334335-32-8
• Molecular Formula: C₂₀H₂₂O₂
• Molecular Weight: 294.393
• Mol file: 1334335-32-8.mol

Synonyms:

Chemical Property of C₂₀H₂₂O₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₀H₂₂O₂

There total 1 articles about C₂₀H₂₂O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

allyl bromide (106-95-6) + (+/-)-1-(4-benzyloxyphenyl)but-3-en-1-ol (470665-14-6) → C20H22O2 (1334335-32-8)

Guidance literature:

(+/-)-1-(4-benzyloxyphenyl)but-3-en-1-ol; With sodium hydride; In N,N-dimethyl-formamide;

allyl bromide; In N,N-dimethyl-formamide; at 20 ℃; for 1h;

DOI:10.1016/j.bmcl.2011.07.006

Reference yield:

C20H22O2 (1334335-32-8) → C14H19ClO2

Guidance literature:

Multi-step reaction with 3 steps

1: tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride / dichloromethane / 24 h / Reflux

2: palladium 10% on activated carbon; hydrogen / ethanol / 15 h / 20 °C / 2250.23 Torr

3: potassium carbonate / N,N-dimethyl-formamide / 20 h / 20 °C

With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; palladium 10% on activated carbon; hydrogen; potassium carbonate; In ethanol; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2011.07.006

Reference yield:

C20H22O2 (1334335-32-8) → C19H29NO2 (1334335-25-9)

Guidance literature:

Multi-step reaction with 4 steps

1: tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride / dichloromethane / 24 h / Reflux

2: palladium 10% on activated carbon; hydrogen / ethanol / 15 h / 20 °C / 2250.23 Torr

3: potassium carbonate / N,N-dimethyl-formamide / 20 h / 20 °C

4: potassium carbonate; potassium iodide / N,N-dimethyl-formamide / 5 h / 60 °C

With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; palladium 10% on activated carbon; hydrogen; potassium carbonate; potassium iodide; In ethanol; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2011.07.006

upstream raw materials:

allyl bromide

(+/-)-1-(4-benzyloxyphenyl)but-3-en-1-ol

Downstream raw materials:

C₁₉H₂₉NO₂

C₁₁H₁₄O₂