N²-isobutyryl-2’,3’-O-isopropylidene-5’-S-[(4-methoxyphenyl)diphenylmethyl]-O⁶-[2-(4-nitrophenyl)-ethyl]-5’-thioguanosine-8-methyl-(8¹→5’-S)-N⁴-benzoyl-2’,3’-O-isopropylidene-6-{[(4-methoxyphenyl)-diphenylmethoxy]methyl}-5’-thiocytidine

Base Information

• Chemical Name: N²-isobutyryl-2’,3’-O-isopropylidene-5’-S-[(4-methoxyphenyl)diphenylmethyl]-O⁶-[2-(4-nitrophenyl)-ethyl]-5’-thioguanosine-8-methyl-(8¹→5’-S)-N⁴-benzoyl-2’,3’-O-isopropylidene-6-{[(4-methoxyphenyl)-diphenylmethoxy]methyl}-5’-thiocytidine
• CAS No.: 1449295-04-8
• Molecular Formula: C₈₆H₈₅N₉O₁₅S₂
• Molecular Weight: 1548.8

Synonyms:

Chemical Property of N²-isobutyryl-2’,3’-O-isopropylidene-5’-S-[(4-methoxyphenyl)diphenylmethyl]-O⁶-[2-(4-nitrophenyl)-ethyl]-5’-thioguanosine-8-methyl-(8¹→5’-S)-N⁴-benzoyl-2’,3’-O-isopropylidene-6-{[(4-methoxyphenyl)-diphenylmethoxy]methyl}-5’-thiocytidine

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Technology Process of N²-isobutyryl-2’,3’-O-isopropylidene-5’-S-[(4-methoxyphenyl)diphenylmethyl]-O⁶-[2-(4-nitrophenyl)-ethyl]-5’-thioguanosine-8-methyl-(8¹→5’-S)-N⁴-benzoyl-2’,3’-O-isopropylidene-6-{[(4-methoxyphenyl)-diphenylmethoxy]methyl}-5’-thiocytidine

There total 1 articles about N²-isobutyryl-2’,3’-O-isopropylidene-5’-S-[(4-methoxyphenyl)diphenylmethyl]-O⁶-[2-(4-nitrophenyl)-ethyl]-5’-thioguanosine-8-methyl-(8¹→5’-S)-N⁴-benzoyl-2’,3’-O-isopropylidene-6-{[(4-methoxyphenyl)-diphenylmethoxy]methyl}-5’-thiocytidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C40H39N3O7S + N2-isobutyryl-2’,3’-O-isopropylidene-8-{[ (methylsulfonyl)oxy]methyl}-5’-S-[(4-methoxyphenyl)diphenylmethyl]-O6-[2-(4-nitrophenyl)ethyl]-5’-thioguanosine (1449295-01-5) → N2-isobutyryl-2’,3’-O-isopropylidene-5’-S-[(4-methoxyphenyl)diphenylmethyl]-O6-[2-(4-nitrophenyl)-ethyl]-5’-thioguanosine-8-methyl-(81→5’-S)-N4-benzoyl-2’,3’-O-isopropylidene-6-{[(4-methoxyphenyl)-diphenylmethoxy]methyl}-5’-thiocytidine (1449295-04-8)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In dimethyl sulfoxide; for 4h;

DOI:10.1002/hlca.201300043

Reference yield:

N2-isobutyryl-2’,3’-O-isopropylidene-5’-S-[(4-methoxyphenyl)diphenylmethyl]-O6-[2-(4-nitrophenyl)-ethyl]-5’-thioguanosine-8-methyl-(81→5’-S)-N4-benzoyl-2’,3’-O-isopropylidene-6-{[(4-methoxyphenyl)-diphenylmethoxy]methyl}-5’-thiocytidine (1449295-04-8) → C46H53N9O13S2

Guidance literature:

With chlorotriisopropylsilane; trifluoroacetic acid; In dichloromethane; for 0.75h;

DOI:10.1002/hlca.201300043

upstream raw materials:

N²-isobutyryl-2’,3’-O-isopropylidene-8-{[ (methylsulfonyl)oxy]methyl}-5’-S-[(4-methoxyphenyl)diphenylmethyl]-O⁶-[2-(4-nitrophenyl)ethyl]-5’-thioguanosine

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