Technology Process of C27H42N4O8
There total 8 articles about C27H42N4O8 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
tetrabutyl ammonium fluoride;
In
tetrahydrofuran;
at 0 - 20 ℃;
for 4h;
DOI:10.1002/cbic.201000177
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1-hydroxy-7-aza-benzotriazole; triethylamine; HATU / dichloromethane / 5 h / 0 - 20 °C
2: palladium on carbon; hydrogen / methanol / 24 h / 20 °C
3: 1-hydroxy-7-aza-benzotriazole; triethylamine; HATU / dichloromethane / 3.5 h / 0 - 20 °C
4: tetrabutyl ammonium fluoride / tetrahydrofuran / 4 h / 0 - 20 °C
With
1-hydroxy-7-aza-benzotriazole; palladium on carbon; tetrabutyl ammonium fluoride; hydrogen; triethylamine; HATU;
In
tetrahydrofuran; methanol; dichloromethane;
DOI:10.1002/cbic.201000177
- Guidance literature:
-
Multi-step reaction with 5 steps
1: Rh/C; hydrogen; acetic acid / methanol / 24 h / 110 °C / 82745.9 Torr
2: 1-hydroxy-7-aza-benzotriazole; triethylamine; HATU / dichloromethane / 5 h / 0 - 20 °C
3: palladium on carbon; hydrogen / methanol / 24 h / 20 °C
4: 1-hydroxy-7-aza-benzotriazole; triethylamine; HATU / dichloromethane / 3.5 h / 0 - 20 °C
5: tetrabutyl ammonium fluoride / tetrahydrofuran / 4 h / 0 - 20 °C
With
1-hydroxy-7-aza-benzotriazole; Rh/C; palladium on carbon; tetrabutyl ammonium fluoride; hydrogen; acetic acid; triethylamine; HATU;
In
tetrahydrofuran; methanol; dichloromethane;
DOI:10.1002/cbic.201000177