C₂₇H₂₈N₄O₃

Base Information

Chemical Name:C₂₇H₂₈N₄O₃
CAS No.:1175143-49-3
Molecular Formula:C₂₇H₂₈N₄O₃
Molecular Weight:456.544
Hs Code.:

C<sub>27</sub>H<sub>28</sub>N<sub>4</sub>O<sub>3</sub>

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₂₇H₂₈N₄O₃

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Technology Process of C₂₇H₂₈N₄O₃

There total 4 articles about C₂₇H₂₈N₄O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₃₂H₃₆N₄O₅

: 1175143-49-3
C₂₇H₂₈N₄O₃

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃;
DOI:10.1016/j.bmcl.2011.06.112

Reference yield:

: 1175015-50-5
2-chloro-6-methoxy-1-phenyl-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde

: 1175143-49-3
C₂₇H₂₈N₄O₃

Guidance literature:: Multi-step reaction with 4 steps

1: sodium dihydrogenphosphate; sodium chlorite / tert-butyl alcohol / 20 °C

2: 4-methyl-morpholine; O-<[cyano(ethoxycarbonyl)methylene]amino>-1,1,3,3-tetramethyluronium tetrafluoroborate / N,N-dimethyl-formamide / 20 °C

3: 1-methyl-pyrrolidin-2-one; sodium hydride / 20 - 140 °C / Microwave irradiation

4: trifluoroacetic acid / dichloromethane / 20 °C

With 4-methyl-morpholine; 1-methyl-pyrrolidin-2-one; sodium chlorite; sodium dihydrogenphosphate; O-<[cyano(ethoxycarbonyl)methylene]amino>-1,1,3,3-tetramethyluronium tetrafluoroborate; sodium hydride; trifluoroacetic acid; In dichloromethane; N,N-dimethyl-formamide; tert-butyl alcohol;
DOI:10.1016/j.bmcl.2011.06.112

Reference yield:

: 1175015-51-6
2-chloro-6-methoxy-1-phenyl-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid

: 1175143-49-3
C₂₇H₂₈N₄O₃

Guidance literature:: Multi-step reaction with 3 steps

1: 4-methyl-morpholine; O-<[cyano(ethoxycarbonyl)methylene]amino>-1,1,3,3-tetramethyluronium tetrafluoroborate / N,N-dimethyl-formamide / 20 °C

2: 1-methyl-pyrrolidin-2-one; sodium hydride / 20 - 140 °C / Microwave irradiation

3: trifluoroacetic acid / dichloromethane / 20 °C

With 4-methyl-morpholine; 1-methyl-pyrrolidin-2-one; O-<[cyano(ethoxycarbonyl)methylene]amino>-1,1,3,3-tetramethyluronium tetrafluoroborate; sodium hydride; trifluoroacetic acid; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2011.06.112