Technology Process of (+/-)-N-(1-cyclohexylhept-2-ynyl)-N-(3-phenylprop-2-ynyl)amine
There total 3 articles about (+/-)-N-(1-cyclohexylhept-2-ynyl)-N-(3-phenylprop-2-ynyl)amine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: hydrazine hydrate / ethanol / 1 h / Reflux
2: potassium carbonate / N,N-dimethyl-formamide / 3 h / 0 °C
3: palladium diacetate; caesium carbonate / ethanol / 2.5 h / Reflux
With
palladium diacetate; potassium carbonate; caesium carbonate; hydrazine hydrate;
In
ethanol; N,N-dimethyl-formamide;
DOI:10.1055/s-0030-1260098
- Guidance literature:
-
Multi-step reaction with 2 steps
1: potassium carbonate / N,N-dimethyl-formamide / 3 h / 0 °C
2: palladium diacetate; caesium carbonate / ethanol / 2.5 h / Reflux
With
palladium diacetate; potassium carbonate; caesium carbonate;
In
ethanol; N,N-dimethyl-formamide;
DOI:10.1055/s-0030-1260098
- Guidance literature:
-
Multi-step reaction with 4 steps
1: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 20 °C / Cooling
2: hydrazine hydrate / ethanol / 1 h / Reflux
3: potassium carbonate / N,N-dimethyl-formamide / 3 h / 0 °C
4: palladium diacetate; caesium carbonate / ethanol / 2.5 h / Reflux
With
di-isopropyl azodicarboxylate; palladium diacetate; potassium carbonate; caesium carbonate; hydrazine hydrate; triphenylphosphine;
In
tetrahydrofuran; ethanol; N,N-dimethyl-formamide;
1: Mitsunobu reaction;
DOI:10.1055/s-0030-1260098
