Technology Process of (S)-3-(6-acetylnaphthalen-2-ylamino)-2-aminopropanoic acid
There total 11 articles about (S)-3-(6-acetylnaphthalen-2-ylamino)-2-aminopropanoic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogenchloride; water;
at 60 ℃;
for 8h;
DOI:10.1021/jo2007626
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: trifluoroacetic acid / dichloromethane / 3 h / 0 - 20 °C
2.1: pyridine / dichloromethane / 0 - 20 °C
3.1: di-isopropyl azodicarboxylate; triphenylphosphine / toluene / 0 - 20 °C
4.1: water; trifluoroacetic acid / dichloromethane / 0 - 20 °C
4.2: 2 h / 20 °C
5.1: hydrogenchloride; water / 8 h / 60 °C
With
pyridine; hydrogenchloride; di-isopropyl azodicarboxylate; water; triphenylphosphine; trifluoroacetic acid;
In
dichloromethane; toluene;
3.1: Fukuyama-Mitsunobu reaction;
DOI:10.1021/jo2007626
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: di-isopropyl azodicarboxylate; triphenylphosphine / toluene / 0 - 20 °C
2.1: water; trifluoroacetic acid / dichloromethane / 0 - 20 °C
2.2: 2 h / 20 °C
3.1: hydrogenchloride; water / 8 h / 60 °C
With
hydrogenchloride; di-isopropyl azodicarboxylate; water; triphenylphosphine; trifluoroacetic acid;
In
dichloromethane; toluene;
1.1: Fukuyama-Mitsunobu reaction;
DOI:10.1021/jo2007626
