N,N-dibenzyl-N-(2-allyl-7,8-dibenzyloxy-2H-chromen-4-ylmethyl)amine hydrochloride

Base Information

• Chemical Name: N,N-dibenzyl-N-(2-allyl-7,8-dibenzyloxy-2H-chromen-4-ylmethyl)amine hydrochloride
• CAS No.: 1313007-80-5
• Molecular Formula: C₄₁H₃₉NO₃*ClH
• Molecular Weight: 630.226
• Mol file: 1313007-80-5.mol

Synonyms:

Chemical Property of N,N-dibenzyl-N-(2-allyl-7,8-dibenzyloxy-2H-chromen-4-ylmethyl)amine hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N,N-dibenzyl-N-(2-allyl-7,8-dibenzyloxy-2H-chromen-4-ylmethyl)amine hydrochloride

There total 8 articles about N,N-dibenzyl-N-(2-allyl-7,8-dibenzyloxy-2H-chromen-4-ylmethyl)amine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N,N-dibenzyl-N-(2-allyl-7,8-dibenzyloxy-2H-chromen-4-ylmethyl)amine (1313175-12-0) → N,N-dibenzyl-N-(2-allyl-7,8-dibenzyloxy-2H-chromen-4-ylmethyl)amine hydrochloride (1313007-80-5)

Guidance literature:

With hydrogenchloride; In ethanol; dichloromethane; Inert atmosphere;

DOI:10.1002/cmdc.201100010

Reference yield:

7,8-dibenzyloxy-2-oxo-2H-chromene-4-carboxaldehyde (1313007-75-8) → N,N-dibenzyl-N-(2-allyl-7,8-dibenzyloxy-2H-chromen-4-ylmethyl)amine hydrochloride (1313007-80-5)

Guidance literature:

Multi-step reaction with 5 steps

1.1: sodium carbonate / chloroform / 14 h / 20 °C / Inert atmosphere

1.2: 2.5 h / 20 °C / Inert atmosphere; Cooling with ice

2.1: potassium carbonate / N,N-dimethyl-formamide / 110 °C / Inert atmosphere

3.1: diisobutylaluminium hydride / hexane; dichloromethane / 2.17 h / -78 °C / Inert atmosphere

4.1: boron trifluoride diethyl etherate / dichloromethane / 2 h / 20 °C / Inert atmosphere; Cooling with ice

5.1: hydrogenchloride / ethanol; dichloromethane / Inert atmosphere

With hydrogenchloride; boron trifluoride diethyl etherate; diisobutylaluminium hydride; sodium carbonate; potassium carbonate; In ethanol; hexane; dichloromethane; chloroform; N,N-dimethyl-formamide;

DOI:10.1002/cmdc.201100010

Reference yield:

7,8-dibenzyloxy-4-N,N-dibenzylaminomethylchromen-2-one (1313007-77-0) → N,N-dibenzyl-N-(2-allyl-7,8-dibenzyloxy-2H-chromen-4-ylmethyl)amine hydrochloride (1313007-80-5)

Guidance literature:

Multi-step reaction with 3 steps

1: diisobutylaluminium hydride / hexane; dichloromethane / 2.17 h / -78 °C / Inert atmosphere

2: boron trifluoride diethyl etherate / dichloromethane / 2 h / 20 °C / Inert atmosphere; Cooling with ice

3: hydrogenchloride / ethanol; dichloromethane / Inert atmosphere

With hydrogenchloride; boron trifluoride diethyl etherate; diisobutylaluminium hydride; In ethanol; hexane; dichloromethane;

DOI:10.1002/cmdc.201100010

upstream raw materials:

N,N-dibenzyl-N-(2-allyl-7,8-dibenzyloxy-2H-chromen-4-ylmethyl)amine

7,8-dibenzyloxy-2-oxo-2H-chromene-4-carboxaldehyde

4-(N-benzylaminomethyl)-7,8-dibenzyloxychromen-2-one

7,8-dibenzyloxy-4-N,N-dibenzylaminomethylchromen-2-one