HCl*Z-Pheγ(COCH2)(RS)Orn

Base Information

• Chemical Name: HCl*Z-Pheγ(COCH2)(RS)Orn
• CAS No.: 119706-50-2
• Molecular Formula: C₂₃H₂₈N₂O₅*ClH
• Molecular Weight: 448.947
• Mol file: 119706-50-2.mol

Synonyms:

Chemical Property of HCl*Z-Pheγ(COCH2)(RS)Orn

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of HCl*Z-Pheγ(COCH2)(RS)Orn

There total 1 articles about HCl*Z-Pheγ(COCH2)(RS)Orn which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

5(S)-N-(benzyloxycarbonyl)amino-2-(RS)-(2-cyanoethyl)-6-phenyl-4-oxohexanoic acid (119706-44-4,119706-45-5) → HCl*Z-Pheγ(COCH2)(RS)Orn (119706-50-2,119706-51-3)

Guidance literature:

With ammonia; hydrogen; nickel; In methanol; for 7h; under 2068.6 Torr; Ambient temperature;

DOI:10.1016/S0040-4020(01)86018-X

Reference yield: 78.5%

HCl*Z-Pheγ(COCH2)(RS)Orn (119706-50-2,119706-51-3) → 2HCl*Phe ψ(COCH2)(RS)Orn (119706-58-0,119706-59-1)

Guidance literature:

With hydrogenchloride; hydrogen; palladium on activated charcoal; In ethanol; for 8h; under 1551.4 Torr; Ambient temperature;

DOI:10.1016/S0040-4020(01)86018-X

Reference yield: 64.0%

1-amidino-3,5-dimethylpyrazole nitrate (54902-67-9) + HCl-Z-(S)Pheψ(COCH2)(R,S)Orn (119706-50-2,119706-51-3) → HCl-Z-(S)Pheψ(COCH2)(R,S)Arg (139577-42-7,139577-43-8)

Guidance literature:

With triethylamine; In N,N-dimethyl-formamide; for 168h; Ambient temperature; pH 8-9;

DOI:10.1002/ardp.19923250103

upstream raw materials:

5(S)-N-(benzyloxycarbonyl)amino-2-(RS)-(2-cyanoethyl)-6-phenyl-4-oxohexanoic acid

Downstream raw materials:

HCl-Z-(S)Pheψ(COCH2)(R,S)Arg

2HCl*(S)Pheψ(COCH2)(R,S)Arg

2HCl*Phe ψ(COCH2)(RS)Orn