Technology Process of C26H28F2N2O4
There total 15 articles about C26H28F2N2O4 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 10 steps
1: triethylamine / dichloromethane
2: lithium diisopropyl amide
3: dihydrogen peroxide; lithium hydroxide / tetrahydrofuran; water
4: diphenyl phosphoryl azide; triethylamine / toluene
5: palladium on activated charcoal; hydrogen / methanol
6: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / dichloromethane
7: palladium on activated charcoal; hydrogen / ethanol
8: triethylamine / dichloromethane
9: sodium hydride / N,N-dimethyl-formamide
10: trifluoroacetic acid / water
With
diphenyl phosphoryl azide; palladium on activated charcoal; hydrogen; dihydrogen peroxide; sodium hydride; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; trifluoroacetic acid; lithium hydroxide; lithium diisopropyl amide;
In
tetrahydrofuran; methanol; ethanol; dichloromethane; water; N,N-dimethyl-formamide; toluene;
2: Evan's asymmetric alkylation / 4: Curtius rearrangement;
DOI:10.1016/j.bmcl.2012.01.014
- Guidance literature:
-
Multi-step reaction with 9 steps
1: lithium diisopropyl amide
2: dihydrogen peroxide; lithium hydroxide / tetrahydrofuran; water
3: diphenyl phosphoryl azide; triethylamine / toluene
4: palladium on activated charcoal; hydrogen / methanol
5: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / dichloromethane
6: palladium on activated charcoal; hydrogen / ethanol
7: triethylamine / dichloromethane
8: sodium hydride / N,N-dimethyl-formamide
9: trifluoroacetic acid / water
With
diphenyl phosphoryl azide; palladium on activated charcoal; hydrogen; dihydrogen peroxide; sodium hydride; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; trifluoroacetic acid; lithium hydroxide; lithium diisopropyl amide;
In
tetrahydrofuran; methanol; ethanol; dichloromethane; water; N,N-dimethyl-formamide; toluene;
1: Evan's asymmetric alkylation / 3: Curtius rearrangement;
DOI:10.1016/j.bmcl.2012.01.014
- Guidance literature:
-
Multi-step reaction with 8 steps
1: dihydrogen peroxide; lithium hydroxide / tetrahydrofuran; water
2: diphenyl phosphoryl azide; triethylamine / toluene
3: palladium on activated charcoal; hydrogen / methanol
4: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / dichloromethane
5: palladium on activated charcoal; hydrogen / ethanol
6: triethylamine / dichloromethane
7: sodium hydride / N,N-dimethyl-formamide
8: trifluoroacetic acid / water
With
diphenyl phosphoryl azide; palladium on activated charcoal; hydrogen; dihydrogen peroxide; sodium hydride; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; trifluoroacetic acid; lithium hydroxide;
In
tetrahydrofuran; methanol; ethanol; dichloromethane; water; N,N-dimethyl-formamide; toluene;
2: Curtius rearrangement;
DOI:10.1016/j.bmcl.2012.01.014