C₁₄H₁₄O⁽¹⁸⁾O

Base Information

• Chemical Name: C₁₄H₁₄O⁽¹⁸⁾O
• CAS No.: 1334285-05-0
• Molecular Formula: C₁₄H₁₄O₂
• Molecular Weight: 216.265
• Mol file: 1334285-05-0.mol

Synonyms:

Chemical Property of C₁₄H₁₄O⁽¹⁸⁾O

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₄H₁₄O⁽¹⁸⁾O

There total 3 articles about C₁₄H₁₄O⁽¹⁸⁾O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,3-diphenyloxirane (1689-71-0,17619-97-5,25144-18-7,38628-70-5,40102-60-1,1439-07-2) → C14H14O(18)O (1334285-05-0)

Guidance literature:

Multi-step reaction with 2 steps

1: Daicel Chiralpak IA / hexane; isopropyl alcohol / Resolution of racemate; Inert atmosphere

2: 2-methoxy-ethanol; sodium; ¹⁸O-labeled water / 95 °C / Inert atmosphere

With 2-methoxy-ethanol; sodium; ¹⁸O-labeled water; In hexane; isopropyl alcohol;

DOI:10.1002/anie.201102263

Reference yield:

(R,R)-trans-stilbene epoxide (1439-07-2) → C14H14O(18)O (1334285-05-0)

Guidance literature:

With 2-methoxy-ethanol; sodium; ¹⁸O-labeled water; at 95 ℃; stereoselective reaction; Inert atmosphere;

DOI:10.1002/anie.201102263

Reference yield:

(R,R)-hydroxybenzoin (52340-78-0) → C14H14O(18)O (1334285-05-0)

Guidance literature:

Multi-step reaction with 2 steps

1.1: pyridine; Diphenylphosphinic chloride / 20 °C / Inert atmosphere

1.2: 20 °C / Inert atmosphere

2.1: 2-methoxy-ethanol; sodium; ¹⁸O-labeled water / 95 °C / Inert atmosphere

With pyridine; 2-methoxy-ethanol; sodium; ¹⁸O-labeled water; Diphenylphosphinic chloride;

DOI:10.1002/anie.201102263

upstream raw materials:

2,3-diphenyloxirane

(R,R)-hydroxybenzoin

(R,R)-trans-stilbene epoxide

Refernces