C₁₅H₁₆ClF₃N₄OS

Base Information

• Chemical Name: C₁₅H₁₆ClF₃N₄OS
• CAS No.: 1173910-97-8
• Molecular Formula: C₁₅H₁₆ClF₃N₄OS
• Molecular Weight: 392.832
• Mol file: 1173910-97-8.mol

Synonyms:

Chemical Property of C₁₅H₁₆ClF₃N₄OS

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of C₁₅H₁₆ClF₃N₄OS

There total 1 articles about C₁₅H₁₆ClF₃N₄OS which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C10H16N2OS (1173910-92-3) + 2,4-dichloro-5-trifluoromethylpyrimidine (3932-97-6) → C15H16ClF3N4OS (1173910-97-8)

Guidance literature:

2,4-dichloro-5-trifluoromethylpyrimidine; With zinc(II) chloride; In diethyl ether; 1,2-dichloro-ethane; tert-butyl alcohol; at 5 ℃; for 1h;

C₁₀H₁₆N₂OS; In diethyl ether; 1,2-dichloro-ethane; tert-butyl alcohol; at -5 ℃; for 1h;

With triethylamine; In diethyl ether; 1,2-dichloro-ethane; tert-butyl alcohol; at -5 - 60 ℃; for 24h; regioselective reaction;

DOI:10.1016/j.bmcl.2009.04.093

Reference yield:

C15H16ClF3N4OS (1173910-97-8) + (1R,2R)-N,N-dimethylcyclopentane-1,2-diamine (942492-63-9) → C22H31F3N6OS (1173911-01-7)

Guidance literature:

With sodium carbonate; In N,N-dimethyl-formamide; at 85 ℃; for 3h;

DOI:10.1016/j.bmcl.2009.04.093

upstream raw materials:

C₁₀H₁₆N₂OS

2,4-dichloro-5-trifluoromethylpyrimidine

Downstream raw materials:

C₂₂H₃₁F₃N₆OS