(4S,14S)-4,14-diisopropyl-19-methyl-21-(benzylthio)-6,9,12-trioxa-3,15,19-triazabicyclo<15.3.1>heneicosa-17,20-diene-2,5,13,16-tetraone

Base Information

• Chemical Name: (4S,14S)-4,14-diisopropyl-19-methyl-21-(benzylthio)-6,9,12-trioxa-3,15,19-triazabicyclo<15.3.1>heneicosa-17,20-diene-2,5,13,16-tetraone
• CAS No.: 92010-75-8
• Molecular Formula: C₂₉H₃₉N₃O₇S
• Molecular Weight: 573.711
• Mol file: 92010-75-8.mol

Synonyms:

Chemical Property of (4S,14S)-4,14-diisopropyl-19-methyl-21-(benzylthio)-6,9,12-trioxa-3,15,19-triazabicyclo<15.3.1>heneicosa-17,20-diene-2,5,13,16-tetraone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (4S,14S)-4,14-diisopropyl-19-methyl-21-(benzylthio)-6,9,12-trioxa-3,15,19-triazabicyclo<15.3.1>heneicosa-17,20-diene-2,5,13,16-tetraone

There total 1 articles about (4S,14S)-4,14-diisopropyl-19-methyl-21-(benzylthio)-6,9,12-trioxa-3,15,19-triazabicyclo<15.3.1>heneicosa-17,20-diene-2,5,13,16-tetraone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(4S,14S)-4,14-di-(2-propyl)-19-methyl-6,9,12-trioxa-3,15-diaza-19-azoniabicyclo<15.3.1>heneicosa-1(21),17,19-triene-2,5,13,16-tetraone perchlorate + phenylmethanethiol (100-53-8) → (4S,14S)-4,14-diisopropyl-19-methyl-21-(benzylthio)-6,9,12-trioxa-3,15,19-triazabicyclo<15.3.1>heneicosa-17,20-diene-2,5,13,16-tetraone (92010-75-8)

Guidance literature:

With methanol; sodium methylate; for 0.0833333h; Ambient temperature;

DOI:10.1021/ja00332a047

Reference yield:

salicylaldehyde (90-02-8) + (4S,14S)-4,14-diisopropyl-19-methyl-21-(benzylthio)-6,9,12-trioxa-3,15,19-triazabicyclo<15.3.1>heneicosa-17,20-diene-2,5,13,16-tetraone (92010-75-8) → 2-(Benzylsulfanyl-hydroxy-methyl)-phenol

Guidance literature:

With ammonium chloride;

DOI:10.1021/ja00332a047

Reference yield:

N-benzyloxycarbonyl-L-phenylalanine p-nitrophenyl ester (2578-84-9) + (4S,14S)-4,14-diisopropyl-19-methyl-21-(benzylthio)-6,9,12-trioxa-3,15,19-triazabicyclo<15.3.1>heneicosa-17,20-diene-2,5,13,16-tetraone (92010-75-8) → S-benzyl (2S)-2-{[(benzyloxy)carbonyl]amino}-3-phenylpropanethioate + 4-Nitro-phenolate(4S,14S)-4,14-diisopropyl-19-methyl-2,5,13,16-tetraoxo-6,9,12-trioxa-3,15-diaza-19-azonia-bicyclo[15.3.1]henicosa-1(20),17(21),18-triene;

Guidance literature:

In acetonitrile; at 25 ℃; Rate constant; other solvents;

DOI:10.1021/ja00332a047

upstream raw materials:

phenylmethanethiol