2'-O-acetyl-3'-O-benzyl-5'-deoxy-5'-ethoxycarbonylmethylcytidine

Base Information

• Chemical Name: 2'-O-acetyl-3'-O-benzyl-5'-deoxy-5'-ethoxycarbonylmethylcytidine
• CAS No.: 1204744-84-2
• Molecular Formula: C₂₂H₂₇N₃O₇
• Molecular Weight: 445.472
• Mol file: 1204744-84-2.mol

Synonyms:

Chemical Property of 2'-O-acetyl-3'-O-benzyl-5'-deoxy-5'-ethoxycarbonylmethylcytidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 2'-O-acetyl-3'-O-benzyl-5'-deoxy-5'-ethoxycarbonylmethylcytidine

There total 1 articles about 2'-O-acetyl-3'-O-benzyl-5'-deoxy-5'-ethoxycarbonylmethylcytidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.6%

3-O-benzyl-5-deoxy-1,2-di-O-acetyl-5-ethoxycarbonylmethyl-D-ribofuranose (1204744-82-0) + cytosine (71-30-7,66398-98-9,66460-16-0) → 2'-O-acetyl-3'-O-benzyl-5'-deoxy-5'-ethoxycarbonylmethylcytidine (1204744-84-2)

Guidance literature:

3-O-benzyl-5-deoxy-1,2-di-O-acetyl-5-ethoxycarbonylmethyl-D-ribofuranose; cytosine; With N,O-bis-(trimethylsilyl)-acetamide; trimethylsilyl trifluoromethanesulfonate; In acetonitrile; for 4h; Reflux;

With water; sodium hydrogencarbonate; for 0.5h;

DOI:10.1134/S1068162009050082

upstream raw materials:

3-O-benzyl-5-deoxy-1,2-di-O-acetyl-5-ethoxycarbonylmethyl-D-ribofuranose

cytosine