2-amino-1-(2-bromobenzyl)-3-(4-fluorophenylsulfonyl)-4,5-dimethylpyrrole

Base Information

Chemical Name:2-amino-1-(2-bromobenzyl)-3-(4-fluorophenylsulfonyl)-4,5-dimethylpyrrole
CAS No.:1313429-71-8
Molecular Formula:C₁₉H₁₈BrFN₂O₂S
Molecular Weight:437.333
Hs Code.:

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-amino-1-(2-bromobenzyl)-3-(4-fluorophenylsulfonyl)-4,5-dimethylpyrrole

Chemical Property:

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Technology Process of 2-amino-1-(2-bromobenzyl)-3-(4-fluorophenylsulfonyl)-4,5-dimethylpyrrole

There total 2 articles about 2-amino-1-(2-bromobenzyl)-3-(4-fluorophenylsulfonyl)-4,5-dimethylpyrrole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3959-05-5
2-bromobenzylamine

: 1313429-71-8
2-amino-1-(2-bromobenzyl)-3-(4-fluorophenylsulfonyl)-4,5-dimethylpyrrole

Guidance literature:: Multi-step reaction with 2 steps

1: Heating

2: ethanol / 2 h / Reflux

In ethanol;
DOI:10.1002/jhet.534

Reference yield:

: 32083-66-2
(4-fluoro-benzenesulphonyl)-acetonitrile

: C₁₁H₁₄BrNO

: 1313429-71-8
2-amino-1-(2-bromobenzyl)-3-(4-fluorophenylsulfonyl)-4,5-dimethylpyrrole

Guidance literature:: In ethanol; for 2h; Reflux;
DOI:10.1002/jhet.534

Reference yield: 49.0%

: 1313429-71-8
2-amino-1-(2-bromobenzyl)-3-(4-fluorophenylsulfonyl)-4,5-dimethylpyrrole

: 1313429-67-2
3-(4-fluorophenylsulfonyl)-1,2-dimethyl-4,9-dihydropyrrolo[2,1-b]quinazoline

Guidance literature:: With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; caesium carbonate; XPhos; In tert-butyl alcohol; for 4h; Reflux; Inert atmosphere;
DOI:10.1002/jhet.534