B-Norcholest-4-en-3-one

Base Information

• Chemical Name: B-Norcholest-4-en-3-one
• CAS No.: 2552-26-3
• Molecular Formula: C₂₆H₄₂O
• Molecular Weight: 370.619
• NSC Number: 50905
• UNII: 2DF7X515LU
• Nikkaji Number: J2.793.048D
• Wikidata: Q27148760
• Mol file: 2552-26-3.mol

Synonyms:B-Norcholest-4-en-3-one;2552-26-3;NSC-50905;2DF7X515LU;UNII-2DF7X515LU;(3r,3ar,5as,5br,10as,10bs)-3a,5b-dimethyl-3-[(2r)-6-methylheptan-2-yl]-2,3,3a,4,5,5a,5b,6,7,10,10a,10b-dodecahydrocyclopenta[a]fluoren-8(1h)-one;7-norcholest-4-en-3-one;CHEBI:79638;NSC50905;Q27148760

Chemical Property of B-Norcholest-4-en-3-one

Chemical Property:

• Vapor Pressure: 5.88E-09mmHg at 25°C
• XLogP3: 8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 5
• Exact Mass: 370.323565959
• Heavy Atom Count: 27
• Complexity: 616

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(C)CCCC(C)C1CCC2C1(CCC3C2CC4=CC(=O)CCC34C)C
• Isomeric SMILES: C[C@H](CCCC(C)C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC4=CC(=O)CC[C@]34C)C

Technology Process of B-Norcholest-4-en-3-one

There total 15 articles about B-Norcholest-4-en-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

B-nor cholesterol (6544-70-3) → B-Nor-cholesten-(4)-on-(3) (2552-26-3)

Guidance literature:

With aluminum tri-tert-butoxide; acetone; benzene; at 75 - 80 ℃;

Reference yield:

3β-acetoxy-B-norcholest-5-ene (14291-09-9) → B-Nor-cholesten-(4)-on-(3) (2552-26-3)

Guidance literature:

Multi-step reaction with 2 steps

1: aqueous methanol. KOH

2: acetone; aluminium tert-butylate; benzene / 75 - 80 °C

With potassium hydroxide; aluminum tri-tert-butoxide; acetone; benzene;

Reference yield:

4β-Brom-B-nor-5β-cholestan-3-on (2449-82-3) → B-Nor-cholesten-(4)-on-(3) (2552-26-3)

Guidance literature:

With 2,3,5-trimethyl-pyridine; at 180 ℃;

upstream raw materials:

B-nor cholesterol

aluminum tri-tert-butoxide

acetone

benzene