trans-3-Azabicyclo<3.3.0>octan

Base Information

• Chemical Name: trans-3-Azabicyclo<3.3.0>octan
• CAS No.: 10268-00-5
• Molecular Formula: C₇H₁₃N
• Molecular Weight: 111.187
• Mol file: 10268-00-5.mol

Synonyms:

Chemical Property of trans-3-Azabicyclo<3.3.0>octan

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of trans-3-Azabicyclo<3.3.0>octan

There total 14 articles about trans-3-Azabicyclo<3.3.0>octan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

N-benzyl-3-aza<3.3.0>bicyclooctane (118989-10-9) → octahydrocyclopenta[c]pyrrole (1468-87-7,5661-03-0,10268-00-5)

Guidance literature:

With ammonium formate; palladium on activated charcoal; In methanol;

DOI:10.1016/S0040-4020(01)87128-3

Reference yield: 80.8%

hexahydrocyclopenta[c]pyrrole-1(2H)-one (56593-76-1) → octahydrocyclopenta[c]pyrrole (1468-87-7,5661-03-0,10268-00-5)

Guidance literature:

With sodium bis(2-methoxyethoxy)aluminium dihydride; In toluene; at 20 - 50 ℃; for 22h; Time;

Reference yield:

cyclopent-1-ene-1,2-dicarbonitrile (54095-53-3) → octahydrocyclopenta[c]pyrrole (1468-87-7,5661-03-0,10268-00-5)

Guidance literature:

With rhodium contaminated with carbon; hydrogen; In tetrahydrofuran; at 130 ℃; for 11h; under 41254.1 Torr; Reagent/catalyst; Time; Temperature; Pressure; Concentration; Autoclave;

upstream raw materials:

N-benzyl-3-aza<3.3.0>bicyclooctane

N-chloro-3-azabicyclo[3.3.0]octane

N-(1'-hydroxy-2'-butyl)-3-aza-3,3,0-bicyclooctane

N-(1'-tert-butoxy-2'-butyl)-3-aza<3,3,0>bicyclooctane

Downstream raw materials:

N-amino-aza-3-bicyclo<3.3.0>octane

N-chloro-3-azabicyclo[3.3.0]octane

N-(4-Cyanophenyl)-N-(4-hexahydrocyclopenta[c]pyrrol-2(1H)-ylbutyl)-acetamide

(3aS,6aR)-1,3a,4,5,6,6a-hexahydrocyclopenta[c]pyrrole