18-Methyleicosanoic acid

Base Information

• Chemical Name: 18-Methyleicosanoic acid
• CAS No.: 36332-93-1
• Molecular Formula: C₂₁H₄₂O₂
• Molecular Weight: 326.563
• UNII: 7STP871R4S
• DSSTox Substance ID: DTXSID201312907
• Nikkaji Number: J1.315.398A
• Wikidata: Q27158144
• Metabolomics Workbench ID: 89
• Mol file: 36332-93-1.mol

Synonyms:18-MEA;18-methyleicosanoic acid

Chemical Property of 18-Methyleicosanoic acid

Chemical Property:

• XLogP3: 9.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 18
• Exact Mass: 326.318480578
• Heavy Atom Count: 23
• Complexity: 250

Purity/Quality:

98.5% ^*data from raw suppliers

(?±)-18-Methyl-d3-eicosanoicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC(C)CCCCCCCCCCCCCCCCC(=O)O
• Description: 18-methyl Eicosanoic acid is a main component of the outer layer of the epicuticle of human hair and endows hydrophobicity to the outer hair surface. It is used as an additive to hair cosmetics due to its desirable conditioning effects.
• Uses: 18-methyl Eicosanoic acid is a main component of the outer layer of the epicuticle of human hair and endows hydrophobicity to the outer hair surface. It is used as an additive to hair cosmetics due to its desirable conditioning effects.

Technology Process of 18-Methyleicosanoic acid

There total 18 articles about 18-Methyleicosanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

→ 18-methyl-eicosanoic acid (36332-93-1)

Guidance literature:

Reference yield: 88.0%

Methyl (+/-)-18-methyleicosanoate (65301-92-0) → 18-methyl-eicosanoic acid (36332-93-1)

Guidance literature:

With potassium hydroxide; In ethanol; at 20 ℃; for 17h;

DOI:10.1080/00304940009356760

Reference yield: 59.0%

sodium hydroxide-ethanol + methyl 18-methyl-16-eicosenoate → 18-methyl-eicosanoic acid (36332-93-1)

Guidance literature:

With sulfuric acid; acetic acid;

upstream raw materials:

Methyl (+/-)-18-methyleicosanoate

pentadecanolide

methyl 15-hydroxypentadecanoate

3-methyl-1-pentanol