(12α,13α,15β,20β)-13-Cyan-2,3,4,5,6,7,8,9,10,11,12,13-dodecahydro-13-phenyl-12,15-methano-15H-1,14-dioxabenzo

cycloheptadecin-20-carbonsaeure-methylester

Base Information

• Chemical Name: (12α,13α,15β,20β)-13-Cyan-2,3,4,5,6,7,8,9,10,11,12,13-dodecahydro-13-phenyl-12,15-methano-15H-1,14-dioxabenzo
• CAS No.: 77733-89-2
• Molecular Formula: C₂₉H₃₅NO₄
• Molecular Weight: 461.601
• Mol file: 77733-89-2.mol

Synonyms:

Chemical Property of (12α,13α,15β,20β)-13-Cyan-2,3,4,5,6,7,8,9,10,11,12,13-dodecahydro-13-phenyl-12,15-methano-15H-1,14-dioxabenzo

cycloheptadecin-20-carbonsaeure-methylester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (12α,13α,15β,20β)-13-Cyan-2,3,4,5,6,7,8,9,10,11,12,13-dodecahydro-13-phenyl-12,15-methano-15H-1,14-dioxabenzo

cycloheptadecin-20-carbonsaeure-methylester

There total 2 articles about (12α,13α,15β,20β)-13-Cyan-2,3,4,5,6,7,8,9,10,11,12,13-dodecahydro-13-phenyl-12,15-methano-15H-1,14-dioxabenzo

cycloheptadecin-20-carbonsaeure-methylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(E)-13-[2-(3-Cyano-3-phenyl-oxiranyl)-phenoxy]-tridec-2-enoic acid methyl ester (77733-84-7) → (2S,4R,5S,6S)-4-Cyano-4-phenyl-3,17-dioxa-tricyclo[16.4.0.02,6]docosa-1(22),18,20-triene-5-carboxylic acid methyl ester (77733-88-1) + (12α,13α,15β,20β)-13-Cyan-2,3,4,5,6,7,8,9,10,11,12,13-dodecahydro-13-phenyl-12,15-methano-15H-1,14-dioxabenzo (77733-89-2)

Guidance literature:

In 2,2,4-trimethylpentane; at 230 ℃; for 10.5h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

DOI:10.1016/S0040-4039(00)71152-X

Reference yield:

(2E)-13-<2-(3-Cyan-trans-3-phenyl-2-oxiranyl)phenoxy>-2-tridecensaeure-methylester (77733-84-7,88081-32-7,88081-36-1,88081-45-2,88081-48-5) → (2S,4R,5S,6S)-4-Cyano-4-phenyl-3,17-dioxa-tricyclo[16.4.0.02,6]docosa-1(22),18,20-triene-5-carboxylic acid methyl ester (77733-88-1) + (12α,13α,15β,20β)-13-Cyan-2,3,4,5,6,7,8,9,10,11,12,13-dodecahydro-13-phenyl-12,15-methano-15H-1,14-dioxabenzo (77733-89-2) + (2E)-13-<2-(3-Cyan-cis-3-phenyl-2-oxiranyl)phenoxy>-2-tridecensaeure-methylester (77733-84-7,88081-32-7,88081-36-1,88081-45-2,88081-48-5)

Guidance literature:

In 2,2,4-trimethylpentane; at 230 ℃; for 10.5h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

upstream raw materials:

(E)-13-[2-(3-Cyano-3-phenyl-oxiranyl)-phenoxy]-tridec-2-enoic acid methyl ester

(2E)-13-<2-(3-Cyan-trans-3-phenyl-2-oxiranyl)phenoxy>-2-tridecensaeure-methylester