Acetic acid (5S,6R,8R,9S,10R,13S,14S,17S)-3-acetoxy-17-acetyl-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-6-yl ester

Base Information

• Chemical Name: Acetic acid (5S,6R,8R,9S,10R,13S,14S,17S)-3-acetoxy-17-acetyl-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-6-yl ester
• CAS No.: 14283-69-3
• Molecular Formula: C₂₅H₃₈O₅
• Molecular Weight: 418.574
• Mol file: 14283-69-3.mol

Synonyms:

Chemical Property of Acetic acid (5S,6R,8R,9S,10R,13S,14S,17S)-3-acetoxy-17-acetyl-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-6-yl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Acetic acid (5S,6R,8R,9S,10R,13S,14S,17S)-3-acetoxy-17-acetyl-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-6-yl ester

There total 10 articles about Acetic acid (5S,6R,8R,9S,10R,13S,14S,17S)-3-acetoxy-17-acetyl-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-6-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(4'-Iodo-biphenyl-3-yl)-acetic acid (5S,6R,8S,9S,10R,13R,14S,17R)-3-acetoxy-17-((R)-1,5-dimethyl-hexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-6-yl ester (105266-38-4) → Acetic acid (5S,6R,8R,9S,10R,13S,14S,17S)-3-acetoxy-17-acetyl-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-6-yl ester (14283-69-3,16826-57-6,37772-22-8,96092-35-2,105368-93-2)

Guidance literature:

Multi-step reaction with 2 steps

1: PhICl₂, 4percent aq. NaHCO₃, 0.3M t-BuOH / CH₂Cl₂ / 1 h / Irradiation

With (Dichloroiodo)benzene; sodium hydrogencarbonate; tert-butyl alcohol; In dichloromethane;

DOI:10.1016/S0040-4039(00)84722-X

Reference yield:

3α,6α-dihydroxy-5α-pregnan-20-one (16134-81-9) + acetic anhydride (108-24-7) → 3α,6α-diacetoxy-5α-pregnanone-(20) (14283-69-3,16826-57-6,37772-22-8,96092-35-2,105368-93-2)

Guidance literature:

With pyridine;

Reference yield:

(4'-Iodo-biphenyl-3-yl)-acetic acid (5S,6R,8R,9S,10R,13S,14S,17S)-3-acetoxy-17-(1-chloro-1,5-dimethyl-hexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-6-yl ester → Acetic acid (5S,6R,8R,9S,10R,13S,14S,17S)-3-acetoxy-17-acetyl-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-6-yl ester (14283-69-3,16826-57-6,37772-22-8,96092-35-2,105368-93-2)

Guidance literature:

Yield given. Multistep reaction;

DOI:10.1016/S0040-4039(00)84722-X

upstream raw materials:

3α,6α-dihydroxy-5α-pregnan-20-one

acetic anhydride

(4'-Iodo-biphenyl-3-yl)-acetic acid (5S,6R,8S,9S,10R,13R,14S,17R)-3-acetoxy-17-((R)-1,5-dimethyl-hexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-6-yl ester