-<2-<<2-<<3-(diethylphosphono)-1-oxopropyl>amino>-2-phenylethyl>amino>-1-(1H-indol-3-ylmethyl)-1-methyl-2-oxoethyl>carbamic acid tricyclo<3.3.1.1^3,7>dec-2-yl ester

Base Information

• Chemical Name: -<2-<<2-<<3-(diethylphosphono)-1-oxopropyl>amino>-2-phenylethyl>amino>-1-(1H-indol-3-ylmethyl)-1-methyl-2-oxoethyl>carbamic acid tricyclo<3.3.1.1^3,7>dec-2-yl ester
• CAS No.: 141956-42-5
• Molecular Formula: C₃₈H₅₁N₄O₇P
• Molecular Weight: 706.819
• Mol file: 141956-42-5.mol

Synonyms:

Chemical Property of -<2-<<2-<<3-(diethylphosphono)-1-oxopropyl>amino>-2-phenylethyl>amino>-1-(1H-indol-3-ylmethyl)-1-methyl-2-oxoethyl>carbamic acid tricyclo<3.3.1.1^3,7>dec-2-yl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of -<2-<<2-<<3-(diethylphosphono)-1-oxopropyl>amino>-2-phenylethyl>amino>-1-(1H-indol-3-ylmethyl)-1-methyl-2-oxoethyl>carbamic acid tricyclo<3.3.1.1^3,7>dec-2-yl ester

There total 1 articles about -<2-<<2-<<3-(diethylphosphono)-1-oxopropyl>amino>-2-phenylethyl>amino>-1-(1H-indol-3-ylmethyl)-1-methyl-2-oxoethyl>carbamic acid tricyclo<3.3.1.1^3,7>dec-2-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

β-diethoxyphosphorylpropionic acid (3095-96-3) + tricyclo<3.3.1.13,7>dec-2-yl *,R*)>-<2-<(2-amino-2-phenylethyl)amino>-1-(1H-indol-3-ylmethyl)-1-methyl-2-oxoethyl>carbamate (130406-64-3) → -<2-<<2-<<3-(diethylphosphono)-1-oxopropyl>amino>-2-phenylethyl>amino>-1-(1H-indol-3-ylmethyl)-1-methyl-2-oxoethyl>carbamic acid tricyclo<3.3.1.13,7>dec-2-yl ester (141956-42-5)

Guidance literature:

With 2,3,4,5,6-pentafluorophenol; dicyclohexyl-carbodiimide; Yield given. Multistep reaction; 1.) EtOAc, RT, 3 h, 2.) EtOAc, RT, overnight;

DOI:10.1021/jm00092a007

Reference yield:

-<2-<<2-<<3-(diethylphosphono)-1-oxopropyl>amino>-2-phenylethyl>amino>-1-(1H-indol-3-ylmethyl)-1-methyl-2-oxoethyl>carbamic acid tricyclo<3.3.1.13,7>dec-2-yl ester (141956-42-5) → -<1-(1H-indol-3-ylmethyl)-1-methyl-2-oxo-2-<<2-<(1-oxo-3-phosphonopropyl)amino>ethyl>amino>ethyl>carbamic acid tricyclo<3.3.1.13,7>dec-2-yl ester (141956-44-7)

Guidance literature:

With trimethylsilyl bromide; water; Yield given. Multistep reaction; 1.) CH₂Cl₂, RT, 36 h, 2.) MeOH, RT, 24 h;

DOI:10.1021/jm00092a007

upstream raw materials:

β-diethoxyphosphorylpropionic acid

tricyclo<3.3.1.1^3,7>dec-2-yl *,R^*)>-<2-<(2-amino-2-phenylethyl)amino>-1-(1H-indol-3-ylmethyl)-1-methyl-2-oxoethyl>carbamate

Downstream raw materials:

-<1-(1H-indol-3-ylmethyl)-1-methyl-2-oxo-2-<<2-<(1-oxo-3-phosphonopropyl)amino>ethyl>amino>ethyl>carbamic acid tricyclo<3.3.1.1^3,7>dec-2-yl ester