Technology Process of 195,245-dibenzyloxy-4,7,13,16,20,23-hexaoxa-1,10-diaza-19(1,2),24(1,2)-dibenzenabicyclo<8.8.6>tetracosaphane-194,244-dicarbaldehyde
There total 8 articles about 195,245-dibenzyloxy-4,7,13,16,20,23-hexaoxa-1,10-diaza-19(1,2),24(1,2)-dibenzenabicyclo<8.8.6>tetracosaphane-194,244-dicarbaldehyde which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
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157700-34-0
194,244-dibenzyloxy-4,7,13,16,20,23-hexaoxa-1,10-diaza-19(1,2),24(1,2)-dibenzenabicyclo<8.8.6>tetracosaphane
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157700-35-1
195,245-dibenzyloxy-4,7,13,16,20,23-hexaoxa-1,10-diaza-19(1,2),24(1,2)-dibenzenabicyclo<8.8.6>tetracosaphane-194,244-dicarbaldehyde
- Guidance literature:
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With
trichlorophosphate;
for 3h;
Ambient temperature;
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157700-35-1
195,245-dibenzyloxy-4,7,13,16,20,23-hexaoxa-1,10-diaza-19(1,2),24(1,2)-dibenzenabicyclo<8.8.6>tetracosaphane-194,244-dicarbaldehyde
- Guidance literature:
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Multi-step reaction with 7 steps
1: 80 percent / K2CO3 / dimethylformamide / 120 °C
2: 91 percent / H2 / 5percent Pt/C / tetrahydrofuran; methanol / 3 h / Ambient temperature
3: 60 percent / Et3N / tetrahydrofuran / 24 h / 0 °C
4: 77 percent / LiAlH4 / tetrahydrofuran / Heating
5: 43 percent / pyridine / tetrahydrofuran / 48 h
6: 1.) B2H6, 2.) aq. HCl / 1.) THF, reflux, 1.5 h
7: 88 percent / POCl3 / 3 h / Ambient temperature
With
pyridine; hydrogenchloride; lithium aluminium tetrahydride; hydrogen; potassium carbonate; triethylamine; diborane; trichlorophosphate;
platinum on activated charcoal;
In
tetrahydrofuran; methanol; N,N-dimethyl-formamide;
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157700-35-1
195,245-dibenzyloxy-4,7,13,16,20,23-hexaoxa-1,10-diaza-19(1,2),24(1,2)-dibenzenabicyclo<8.8.6>tetracosaphane-194,244-dicarbaldehyde
- Guidance literature:
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Multi-step reaction with 6 steps
1: 91 percent / H2 / 5percent Pt/C / tetrahydrofuran; methanol / 3 h / Ambient temperature
2: 60 percent / Et3N / tetrahydrofuran / 24 h / 0 °C
3: 77 percent / LiAlH4 / tetrahydrofuran / Heating
4: 43 percent / pyridine / tetrahydrofuran / 48 h
5: 1.) B2H6, 2.) aq. HCl / 1.) THF, reflux, 1.5 h
6: 88 percent / POCl3 / 3 h / Ambient temperature
With
pyridine; hydrogenchloride; lithium aluminium tetrahydride; hydrogen; triethylamine; diborane; trichlorophosphate;
platinum on activated charcoal;
In
tetrahydrofuran; methanol;
