(+/-)-2,2'-bis(diphenylphosphino)-1,1'-bibenzimidazole

Base Information

• Chemical Name: (+/-)-2,2'-bis(diphenylphosphino)-1,1'-bibenzimidazole
• CAS No.: 175871-67-7
• Molecular Formula: C₃₈H₂₈N₄P₂
• Molecular Weight: 602.615
• Mol file: 175871-67-7.mol

Synonyms:

Chemical Property of (+/-)-2,2'-bis(diphenylphosphino)-1,1'-bibenzimidazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+/-)-2,2'-bis(diphenylphosphino)-1,1'-bibenzimidazole

There total 3 articles about (+/-)-2,2'-bis(diphenylphosphino)-1,1'-bibenzimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

chloro-diphenylphosphine (1079-66-9,74391-44-9) + bicyclobenzimidazole (75261-44-8) → (+/-)-2,2'-bis(diphenylphosphino)-1,1'-bibenzimidazole (175871-67-7,175871-68-8,175871-69-9)

Guidance literature:

With n-butyllithium; N,N,N,N,-tetramethylethylenediamine; In tetrahydrofuran; hexane; at 0 ℃; for 2h;

DOI:10.1016/S0022-328X(96)06682-X

Reference yield:

2,2'-dimethyl-1,1'-bibenzimidazole (77436-45-4) → (+/-)-2,2'-bis(diphenylphosphino)-1,1'-bibenzimidazole (175871-67-7,175871-68-8,175871-69-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 98 percent / SeO₂ / dioxane / 5 h / 80 °C

2: 62 percent / KMnO₄, Na₂CO₃ / H₂O; benzene / 10 h / 25 °C

3: 78 percent / BuLi, N,N,N',N'-tetramethylethylenediamine / hexane; tetrahydrofuran / 2 h / 0 °C

With potassium permanganate; n-butyllithium; selenium(IV) oxide; N,N,N,N,-tetramethylethylenediamine; sodium carbonate; In tetrahydrofuran; 1,4-dioxane; hexane; water; benzene;

DOI:10.1016/S0022-328X(96)06682-X

Reference yield:

1,1'-bibenzimidazolyl-2,2'-dicarboxaldehyde (175871-66-6) → (+/-)-2,2'-bis(diphenylphosphino)-1,1'-bibenzimidazole (175871-67-7,175871-68-8,175871-69-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 62 percent / KMnO₄, Na₂CO₃ / H₂O; benzene / 10 h / 25 °C

2: 78 percent / BuLi, N,N,N',N'-tetramethylethylenediamine / hexane; tetrahydrofuran / 2 h / 0 °C

With potassium permanganate; n-butyllithium; N,N,N,N,-tetramethylethylenediamine; sodium carbonate; In tetrahydrofuran; hexane; water; benzene;

DOI:10.1016/S0022-328X(96)06682-X

upstream raw materials:

chloro-diphenylphosphine

bicyclobenzimidazole

2,2'-dimethyl-1,1'-bibenzimidazole

1,1'-bibenzimidazolyl-2,2'-dicarboxaldehyde

Downstream raw materials:

((C₆H₅)2PC₇H₄N₂)2PdCl₂

Pt(C₆H₅)2PC₂₀H₁₂P(C₆H₅)2Cl₂