trans-4-iodocyclohexanol

Base Information

• Chemical Name: trans-4-iodocyclohexanol
• CAS No.: 146651-22-1
• Molecular Formula: C₆H₁₁IO
• Molecular Weight: 226.057
• Mol file: 146651-22-1.mol

Synonyms:

Chemical Property of trans-4-iodocyclohexanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of trans-4-iodocyclohexanol

There total 1 articles about trans-4-iodocyclohexanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

7-oxabicyclo(2.2.1)heptane (279-49-2) → trans-4-iodocyclohexanol (146651-22-1)

Guidance literature:

With hydrogen iodide; for 1h; Ambient temperature;

DOI:10.1021/jo00057a034

Reference yield:

trans-4-iodocyclohexanol (146651-22-1) → 3α-hydroxy-5β-cholan-24-oic acid trans-4-iodocyclohexyl ester

Guidance literature:

Multi-step reaction with 2 steps

1: 38 percent / (dimethylamino)pyridine, dicyclohexylcarbodiimide / diethyl ether / 12 h / Ambient temperature

2: 97 percent / 50percent aq. HF / acetonitrile / Heating

With dmap; hydrogen fluoride; dicyclohexyl-carbodiimide; In diethyl ether; acetonitrile;

DOI:10.1021/jo00057a034

upstream raw materials:

7-oxabicyclo(2.2.1)heptane