[(1R,2R,3S)-2-{3-[(1R,2R,3S)-2-(4-Ethoxy-benzoyl)-3-(toluene-4-sulfonyl)-cyclopropyl]-phenyl}-3-(toluene-4-sulfonyl)-cyclopropyl]-(4-ethoxy-phenyl)-methanone

Base Information

Chemical Name:[(1R,2R,3S)-2-{3-[(1R,2R,3S)-2-(4-Ethoxy-benzoyl)-3-(toluene-4-sulfonyl)-cyclopropyl]-phenyl}-3-(toluene-4-sulfonyl)-cyclopropyl]-(4-ethoxy-phenyl)-methanone
CAS No.:143517-29-7
Molecular Formula:C₄₄H₄₂O₈S₂
Molecular Weight:762.945
Hs Code.:

[(1R,2R,3S)-2-{3-[(1R,2R,3S)-2-(4-Ethoxy-benzoyl)-3-(toluene-4-sulfonyl)-cyclopropyl]-phenyl}-3-(toluene-4-sulfonyl)-cyclopropyl]-(4-ethoxy-phenyl)-methanone

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Chemical Property of [(1R,2R,3S)-2-{3-[(1R,2R,3S)-2-(4-Ethoxy-benzoyl)-3-(toluene-4-sulfonyl)-cyclopropyl]-phenyl}-3-(toluene-4-sulfonyl)-cyclopropyl]-(4-ethoxy-phenyl)-methanone

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Technology Process of [(1R,2R,3S)-2-{3-[(1R,2R,3S)-2-(4-Ethoxy-benzoyl)-3-(toluene-4-sulfonyl)-cyclopropyl]-phenyl}-3-(toluene-4-sulfonyl)-cyclopropyl]-(4-ethoxy-phenyl)-methanone

There total 3 articles about [(1R,2R,3S)-2-{3-[(1R,2R,3S)-2-(4-Ethoxy-benzoyl)-3-(toluene-4-sulfonyl)-cyclopropyl]-phenyl}-3-(toluene-4-sulfonyl)-cyclopropyl]-(4-ethoxy-phenyl)-methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 143517-21-9
((1R,2R,3S)-2-{3-[(1R,2R,3S)-2-(4-Ethoxy-benzoyl)-3-p-tolylsulfanyl-cyclopropyl]-phenyl}-3-p-tolylsulfanyl-cyclopropyl)-(4-ethoxy-phenyl)-methanone

: 143517-29-7
[(1R,2R,3S)-2-{3-[(1R,2R,3S)-2-(4-Ethoxy-benzoyl)-3-(toluene-4-sulfonyl)-cyclopropyl]-phenyl}-3-(toluene-4-sulfonyl)-cyclopropyl]-(4-ethoxy-phenyl)-methanone

Guidance literature:: With dihydrogen peroxide; In acetic acid; for 10h; Heating;

Reference yield:

: 34125-84-3
chloromethyl p-tolyl sulfide

: 143517-29-7
[(1R,2R,3S)-2-{3-[(1R,2R,3S)-2-(4-Ethoxy-benzoyl)-3-(toluene-4-sulfonyl)-cyclopropyl]-phenyl}-3-(toluene-4-sulfonyl)-cyclopropyl]-(4-ethoxy-phenyl)-methanone

Guidance literature:: Multi-step reaction with 2 steps

1: 69 percent / 50percent aq. NaOH, benzyltriethylammonium chloride / CH₂Cl₂ / 16 h / Ambient temperature

2: 67 percent / 30percent H₂O₂ / acetic acid / 10 h / Heating

With sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; dihydrogen peroxide; In dichloromethane; acetic acid;

Reference yield:

: 143517-13-9
(E)-1-(4-Ethoxy-phenyl)-3-{3-[(E)-3-(4-ethoxy-phenyl)-3-oxo-propenyl]-phenyl}-propenone

: 143517-29-7
[(1R,2R,3S)-2-{3-[(1R,2R,3S)-2-(4-Ethoxy-benzoyl)-3-(toluene-4-sulfonyl)-cyclopropyl]-phenyl}-3-(toluene-4-sulfonyl)-cyclopropyl]-(4-ethoxy-phenyl)-methanone

Guidance literature:: Multi-step reaction with 2 steps

1: 69 percent / 50percent aq. NaOH, benzyltriethylammonium chloride / CH₂Cl₂ / 16 h / Ambient temperature

2: 67 percent / 30percent H₂O₂ / acetic acid / 10 h / Heating

With sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; dihydrogen peroxide; In dichloromethane; acetic acid;