9H-fluoren-9-ylmethyl {(2S)-5-amino-1-oxo-1-[(2S)-2-(4-phenyl-1H-imidazol-2-yl)pyrrolidin-1-yl]pentan-2-yl}carbamate

Base Information

• Chemical Name: 9H-fluoren-9-ylmethyl {(2S)-5-amino-1-oxo-1-[(2S)-2-(4-phenyl-1H-imidazol-2-yl)pyrrolidin-1-yl]pentan-2-yl}carbamate
• CAS No.: 1252035-98-5
• Molecular Formula: C₃₃H₃₅N₅O₃
• Molecular Weight: 549.673
• Mol file: 1252035-98-5.mol

Synonyms:

Chemical Property of 9H-fluoren-9-ylmethyl {(2S)-5-amino-1-oxo-1-[(2S)-2-(4-phenyl-1H-imidazol-2-yl)pyrrolidin-1-yl]pentan-2-yl}carbamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 9H-fluoren-9-ylmethyl {(2S)-5-amino-1-oxo-1-[(2S)-2-(4-phenyl-1H-imidazol-2-yl)pyrrolidin-1-yl]pentan-2-yl}carbamate

There total 1 articles about 9H-fluoren-9-ylmethyl {(2S)-5-amino-1-oxo-1-[(2S)-2-(4-phenyl-1H-imidazol-2-yl)pyrrolidin-1-yl]pentan-2-yl}carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2S)-2-(4-phenyl-1H-imidazol-2-yl)pyrrolidine-1-carboxylate hydrochloride + (S)-5-Amino-2-(9H-fluoren-9-ylmethoxycarbonylamino)-pentanoic acid (158599-00-9) → 9H-fluoren-9-ylmethyl {(2S)-5-amino-1-oxo-1-[(2S)-2-(4-phenyl-1H-imidazol-2-yl)pyrrolidin-1-yl]pentan-2-yl}carbamate (1252035-98-5)

Guidance literature:

With dmap; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃;

DOI:10.1021/jm101013m

upstream raw materials:

(S)-5-Amino-2-(9H-fluoren-9-ylmethoxycarbonylamino)-pentanoic acid