C₃₅H₄₂O₆Si

Base Information

• Chemical Name: C₃₅H₄₂O₆Si
• CAS No.: 1255639-83-8
• Molecular Formula: C₃₅H₄₂O₆Si
• Molecular Weight: 586.8
• Mol file: 1255639-83-8.mol

Synonyms:

Chemical Property of C₃₅H₄₂O₆Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₅H₄₂O₆Si

There total 11 articles about C₃₅H₄₂O₆Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

C35H42O6Si (1255639-82-7) → C35H42O6Si (1255639-83-8)

Guidance literature:

In chloroform-d1; for 96h; Inert atmosphere;

DOI:10.1021/ml1001807

Reference yield:

C22H28O2Si (1255639-74-7) → C35H42O6Si (1255639-83-8)

Guidance literature:

Multi-step reaction with 8 steps

1.1: n-butyllithium / tetrahydrofuran / -78 - -10 °C / Inert atmosphere

1.2: -78 - 20 °C / Inert atmosphere

2.1: 1H-imidazole / N,N-dimethyl-formamide / 15 h / 20 °C / Inert atmosphere

3.1: 9-bora-bicyclo[3.3.1]nonane / tetrahydrofuran / 5 h / 20 °C / Inert atmosphere

3.2: Inert atmosphere

3.3: 19 h / Inert atmosphere; Reflux

4.1: hydrogen / ethyl acetate / 0.83 h / 5625.56 Torr / Inert atmosphere

5.1: methanol; water; sodium hydroxide / 21 h / 87 °C / Inert atmosphere

6.1: triphenylphosphine; diethylazodicarboxylate / toluene / 0 - 20 °C / Inert atmosphere

7.1: Jones reagent; potassium fluoride / acetone / 2 h / -10 °C / Inert atmosphere

8.1: chloroform-d1 / 96 h / Inert atmosphere

With 1H-imidazole; methanol; potassium fluoride; Jones reagent; n-butyllithium; water; hydrogen; 9-bora-bicyclo[3.3.1]nonane; triphenylphosphine; sodium hydroxide; diethylazodicarboxylate; In tetrahydrofuran; chloroform-d1; ethyl acetate; N,N-dimethyl-formamide; acetone; toluene; 3.1: Suzuki Miyaura coupling / 3.2: Suzuki Miyaura coupling / 3.3: Suzuki Miyaura coupling / 6.1: Mitsunobu reaction;

DOI:10.1021/ml1001807

Reference yield:

(S)-3-(tert-butyldiphenylsiloxy)hex-5-en-1-ol (1255639-73-6) → C35H42O6Si (1255639-83-8)

Guidance literature:

Multi-step reaction with 9 steps

1.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 1 h / -78 °C / Inert atmosphere

1.2: -78 - 20 °C / Inert atmosphere

2.1: n-butyllithium / tetrahydrofuran / -78 - -10 °C / Inert atmosphere

2.2: -78 - 20 °C / Inert atmosphere

3.1: 1H-imidazole / N,N-dimethyl-formamide / 15 h / 20 °C / Inert atmosphere

4.1: 9-bora-bicyclo[3.3.1]nonane / tetrahydrofuran / 5 h / 20 °C / Inert atmosphere

4.2: Inert atmosphere

4.3: 19 h / Inert atmosphere; Reflux

5.1: hydrogen / ethyl acetate / 0.83 h / 5625.56 Torr / Inert atmosphere

6.1: methanol; water; sodium hydroxide / 21 h / 87 °C / Inert atmosphere

7.1: triphenylphosphine; diethylazodicarboxylate / toluene / 0 - 20 °C / Inert atmosphere

8.1: Jones reagent; potassium fluoride / acetone / 2 h / -10 °C / Inert atmosphere

9.1: chloroform-d1 / 96 h / Inert atmosphere

With 1H-imidazole; methanol; potassium fluoride; Jones reagent; n-butyllithium; oxalyl dichloride; water; hydrogen; dimethyl sulfoxide; 9-bora-bicyclo[3.3.1]nonane; triphenylphosphine; sodium hydroxide; diethylazodicarboxylate; In tetrahydrofuran; chloroform-d1; dichloromethane; ethyl acetate; N,N-dimethyl-formamide; acetone; toluene; 1.1: Swern oxidation / 1.2: Swern oxidation / 4.1: Suzuki Miyaura coupling / 4.2: Suzuki Miyaura coupling / 4.3: Suzuki Miyaura coupling / 7.1: Mitsunobu reaction;

DOI:10.1021/ml1001807

upstream raw materials:

(S)-1-(tert-butyldimethylsiloxy)-3-(tert-butyldiphenylsiloxy)hex-5-ene

(S)-3-(tert-butyldiphenylsiloxy)hex-5-en-1-ol

C₂₂H₂₈O₂Si

C₃₃H₅₀O₃Si₂