(S)-6,6'-Dibromo-2,2',3,3'-tetrahydro-1,1'-spirobi[1H-indene]-7,7'-diol,99%e.e.

Base Information

Chemical Name:(S)-6,6'-Dibromo-2,2',3,3'-tetrahydro-1,1'-spirobi[1H-indene]-7,7'-diol,99%e.e.
CAS No.:1621066-74-7
Molecular Formula:C₁₇H₁₄Br₂O₂
Molecular Weight:410.105
Hs Code.:
Mol file:1621066-74-7.mol

Synonyms:

Suppliers and Price of (S)-6,6'-Dibromo-2,2',3,3'-tetrahydro-1,1'-spirobi[1H-indene]-7,7'-diol,99%e.e.

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Strem Chemicals
(S)-6,6'-Dibromo-2,2',3,3'-tetrahydro-1,1'-spirobi[1H-indene]-7,7'-diol, 98% (99% ee)
250mg
$ 218.00

Crysdot
(S)-6,6'-Dibromo-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol 97%
1g
$ 900.00

Crysdot
(S)-6,6'-Dibromo-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol 97%
100mg
$ 240.00

Total 10 raw suppliers

Chemical Property of (S)-6,6'-Dibromo-2,2',3,3'-tetrahydro-1,1'-spirobi[1H-indene]-7,7'-diol,99%e.e.

Chemical Property:

Boiling Point:449.2±45.0 °C(Predicted)
PKA:8.03±0.20(Predicted)
Density:1.91±0.1 g/cm3(Predicted)

Purity/Quality:

99% ^*data from raw suppliers

(S)-6,6'-Dibromo-2,2',3,3'-tetrahydro-1,1'-spirobi[1H-indene]-7,7'-diol, 98% (99% ee) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-6,6'-Dibromo-2,2',3,3'-tetrahydro-1,1'-spirobi[1H-indene]-7,7'-diol,99%e.e.

There total 2 articles about (S)-6,6'-Dibromo-2,2',3,3'-tetrahydro-1,1'-spirobi[1H-indene]-7,7'-diol,99%e.e. which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 223137-87-9,223259-62-9,223259-63-0
(R)-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol

: 1286189-15-8,1621066-74-7,1807777-59-8
6,6'-dibromo-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol

Guidance literature:: With N-Bromosuccinimide; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 ℃; for 6h; Inert atmosphere;
DOI:10.1021/ja200084a

Reference yield: 70.0%

: (1R)-2,2',3,3'-tetrahydro-1,1'-spirobis[indenyl]-7,7'-diol

: 1621066-74-7,1807777-59-8
(R)-6,6'-dibromo-2,2',3,3'-tetrahydro-1,1'-spirobis[1H-indole]-7,7'-diphenol

Guidance literature:: With N-Bromosuccinimide; potassium hydrogencarbonate; In dichloromethane; at -20 ℃;
DOI:10.1021/jo200302x

Reference yield:

: 1621066-74-7,1807777-59-8
(R)-6,6'-dibromo-2,2',3,3'-tetrahydro-1,1'-spirobis[1H-indole]-7,7'-diphenol

: C₃₇H₂₇O₄P

Guidance literature:: Multi-step reaction with 3 steps

1: tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; potassium phosphate / 1,4-dioxane; toluene / 105 - 110 °C / Inert atmosphere

2: pyridine; trichlorophosphate / Inert atmosphere

3: hydrogenchloride; water; acetic acid / 1,2-dichloro-ethane / Reflux

With pyridine; hydrogenchloride; potassium phosphate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; water; acetic acid; trichlorophosphate; In 1,4-dioxane; 1,2-dichloro-ethane; toluene;
DOI:10.1021/jo200302x