(4,6-Dimethyl-pyridin-2-yl)-thiourea

Base Information

• Chemical Name: (4,6-Dimethyl-pyridin-2-yl)-thiourea
• CAS No.: 49600-35-3
• Molecular Formula: C₈H₁₁N₃S
• Molecular Weight: 181.261
• European Community (EC) Number: 805-965-9
• Mol file: 49600-35-3.mol

Synonyms:(4,6-dimethyl-pyridin-2-yl)-thiourea;49600-35-3;(4,6-dimethylpyridin-2-yl)thiourea;N-(4,6-Dimethyl-2-pyridyl)thiourea;SCHEMBL6178877;(4,6-dimethyl-2-pyridyl)thiourea;AKOS040768749

Chemical Property of (4,6-Dimethyl-pyridin-2-yl)-thiourea

Chemical Property:

• Melting Point: 238-243℃
• XLogP3: 1.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 181.06736854
• Heavy Atom Count: 12
• Complexity: 172

Purity/Quality:

99% ^*data from raw suppliers

(4,6-Dimethyl-pyridin-2-yl)-thiourea 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=CC(=NC(=C1)NC(=S)N)C

Technology Process of (4,6-Dimethyl-pyridin-2-yl)-thiourea

There total 3 articles about (4,6-Dimethyl-pyridin-2-yl)-thiourea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Amino-4,6-dimethylpyridine (5407-87-4) → (4,6-dimethyl-pyridin-2-yl)-thiourea (49600-35-3)

Guidance literature:

Multi-step reaction with 2 steps

1: acetone

2: aq. NaOH

With sodium hydroxide; In acetone;

DOI:10.1016/j.bmcl.2006.04.060

Reference yield:

1-benzoyl-3-(4,6-dimethyl-pyridin-2-yl)-thiourea (102739-48-0) → (4,6-dimethyl-pyridin-2-yl)-thiourea (49600-35-3)

Guidance literature:

With sodium hydroxide;

DOI:10.1016/j.bmcl.2006.04.060

Reference yield:

→ (4,6-dimethyl-pyridin-2-yl)-thiourea (49600-35-3)

Guidance literature:

DOI:10.1007/BF00903919

upstream raw materials:

1-benzoyl-3-(4,6-dimethyl-pyridin-2-yl)-thiourea

2-Amino-4,6-dimethylpyridine