Technology Process of 2-(2-nitrophenyl)but-3-en-1-yl pivalate
There total 2 articles about 2-(2-nitrophenyl)but-3-en-1-yl pivalate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: copper(I) cyanide di(lithium chloride); phenylmagnesium chloride / tetrahydrofuran
2: potassium tert-butylate / dimethyl sulfoxide / 18 h / 20 °C / Inert atmosphere
3: dicyclohexyl-carbodiimide; dmap / dichloromethane / 4 h / Inert atmosphere; Reflux
With
dmap; copper(I) cyanide di(lithium chloride); phenylmagnesium chloride; potassium tert-butylate; dicyclohexyl-carbodiimide;
In
tetrahydrofuran; dichloromethane; dimethyl sulfoxide;
DOI:10.1021/jo4009904
- Guidance literature:
-
Multi-step reaction with 2 steps
1: potassium tert-butylate / dimethyl sulfoxide / 18 h / 20 °C / Inert atmosphere
2: dicyclohexyl-carbodiimide; dmap / dichloromethane / 4 h / Inert atmosphere; Reflux
With
dmap; potassium tert-butylate; dicyclohexyl-carbodiimide;
In
dichloromethane; dimethyl sulfoxide;
DOI:10.1021/jo4009904
- Guidance literature:
-
With
tin(II) chloride dihdyrate;
In
ethanol;
at 20 - 60 ℃;
for 2h;
Inert atmosphere;
DOI:10.1021/jo4009904
