Technology Process of C25H31NO3
There total 2 articles about C25H31NO3 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: water; sulfuric acid / dichloromethane / 0 - 20 °C
2.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C / Inert atmosphere
2.2: 2 h / -78 °C / Inert atmosphere
2.3: 12 h / -78 - 20 °C / Inert atmosphere
3.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 0.5 h / -78 °C / Inert atmosphere
3.2: 0.5 h / -78 - 20 °C / Inert atmosphere
With
n-butyllithium; oxalyl dichloride; sulfuric acid; water; dimethyl sulfoxide;
In
tetrahydrofuran; hexane; dichloromethane;
3.1: |Swern Oxidation / 3.2: |Swern Oxidation;
DOI:10.1016/j.tet.2014.03.055
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C / Inert atmosphere
1.2: 2 h / -78 °C / Inert atmosphere
1.3: 12 h / -78 - 20 °C / Inert atmosphere
2.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 0.5 h / -78 °C / Inert atmosphere
2.2: 0.5 h / -78 - 20 °C / Inert atmosphere
With
n-butyllithium; oxalyl dichloride; dimethyl sulfoxide;
In
tetrahydrofuran; hexane; dichloromethane;
2.1: |Swern Oxidation / 2.2: |Swern Oxidation;
DOI:10.1016/j.tet.2014.03.055
- Guidance literature:
-
Multi-step reaction with 2 steps
1: sodium tetrahydroborate / methanol / -20 - 20 °C / Inert atmosphere
2: lithium aluminium tetrahydride / tetrahydrofuran / 16 h / 0 - 20 °C / Inert atmosphere
With
sodium tetrahydroborate; lithium aluminium tetrahydride;
In
tetrahydrofuran; methanol;
DOI:10.1016/j.tet.2014.03.055
