C₁₃H₇⁽²⁾HN₂

Base Information

• Chemical Name: C₁₃H₇⁽²⁾HN₂
• CAS No.: 887601-41-4
• Molecular Formula: C₁₃H₈N₂
• Molecular Weight: 193.212
• Mol file: 887601-41-4.mol

Synonyms:

Chemical Property of C₁₃H₇⁽²⁾HN₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₃H₇⁽²⁾HN₂

There total 2 articles about C₁₃H₇⁽²⁾HN₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

phenyl(phenylethynyl)iodonium para-toluenesulfonate → C13H7(2)HN2 (887601-41-4)

Guidance literature:

Multi-step reaction with 3 steps

1.1: 29 percent / LiHMDS / tetrahydrofuran; hexane; CH₂Cl₂ / 2 h / 20 °C

2.1: 63 percent / Pd(PPh₃)4; Et₃N; CuI / 0.25 h / 50 °C

3.1: BuLi / diethyl ether; hexane / 0.25 h / -78 °C

3.2: 94 percent / D₂O / diethyl ether; hexane / -78 - 20 °C

With copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; n-butyllithium; triethylamine; lithium hexamethyldisilazane; In tetrahydrofuran; diethyl ether; hexane; dichloromethane; 2.1: Sonogashira coupling;

DOI:10.1016/j.tet.2005.11.084

Reference yield:

2-iodo-1-(phenylethynyl)-1H-imidazole (486999-96-6) → C13H7(2)HN2 (887601-41-4)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 63 percent / Pd(PPh₃)4; Et₃N; CuI / 0.25 h / 50 °C

2.1: BuLi / diethyl ether; hexane / 0.25 h / -78 °C

2.2: 94 percent / D₂O / diethyl ether; hexane / -78 - 20 °C

With copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; n-butyllithium; triethylamine; In diethyl ether; hexane; 1.1: Sonogashira coupling;

DOI:10.1016/j.tet.2005.11.084

Reference yield: 26.0%

C13H7(2)HN2 (887601-41-4) → C13H8(2)HClN2

Guidance literature:

With chlorobenzene; at 100 ℃; for 48h;

DOI:10.1016/j.tet.2005.11.084

upstream raw materials:

2-iodo-1-(phenylethynyl)-1H-imidazole