1-(4-Fluorobenzyl)piperidine

Base Information

Chemical Name:1-(4-Fluorobenzyl)piperidine
CAS No.:139592-92-0
Molecular Formula:C12H16FN
Molecular Weight:193.264
Hs Code.:
DSSTox Substance ID:DTXSID40402403
Nikkaji Number:J446.102I
Wikidata:Q82205810
Mol file:139592-92-0.mol

Synonyms:1-(4-fluorobenzyl)piperidine;139592-92-0;1-[(4-fluorophenyl)methyl]piperidine;SCHEMBL1505875;DTXSID40402403;NRXXCFFOTIFBGX-UHFFFAOYSA-N;STK041684;AKOS003974662;SB42002;CS-0271825;EN300-1197070

Suppliers and Price of 1-(4-Fluorobenzyl)piperidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-(4-Fluorobenzyl)piperidine 97%
5g
$ 1177.00

Crysdot
1-(4-Fluorobenzyl)piperidine 97%
1g
$ 429.00

Total 2 raw suppliers

Chemical Property of 1-(4-Fluorobenzyl)piperidine

Chemical Property:

Boiling Point:252.0±15.0 °C(Predicted)
PSA：3.24000
Density:1.073±0.06 g/cm3(Predicted)
LogP:2.74950
XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:193.126677677
Heavy Atom Count:14
Complexity:158

Purity/Quality:

99% ^*data from raw suppliers

1-(4-Fluorobenzyl)piperidine 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CCN(CC1)CC2=CC=C(C=C2)F

Technology Process of 1-(4-Fluorobenzyl)piperidine

There total 8 articles about 1-(4-Fluorobenzyl)piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 58547-67-4
N-(p-fluorobenzoyl)piperidine

: 139592-92-0
4-fluorobenzylpiperidine

Guidance literature:: With diethylzinc; lithium chloride; In tetrahydrofuran; hexane; at 20 ℃; for 24h; chemoselective reaction; Catalytic behavior; Inert atmosphere;
DOI:10.1021/ol503430t

Reference yield: 98.0%

: 110-89-4
piperidine

: 459-56-3
4-fluorobenzylic alcohol

: 139592-92-0
4-fluorobenzylpiperidine

Guidance literature:: With polystyrene supported triphenylphosphine ruthenium complex; In toluene; at 120 ℃; for 20h; Sealed tube; Flow reactor;
DOI:10.1002/cctc.201300971

Reference yield: 95.0%

: 110-89-4
piperidine

: 459-57-4
4-fluorobenzaldehyde

: 139592-92-0
4-fluorobenzylpiperidine

Guidance literature:: piperidine; 4-fluorobenzaldehyde; With acetic acid; In 1,2-dichloro-ethane; at 20 ℃; for 2h;

With sodium tris(acetoxy)borohydride; In 1,2-dichloro-ethane; at 20 ℃;

With sodium hydrogencarbonate; In water; 1,2-dichloro-ethane;