(6R)-7t-[(R)-2-(4-chloro-phenyl)-2-hydroxy-acetylamino]-3-methyl-8-oxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid; triethylamine salt

Base Information

Chemical Name:(6R)-7t-[(R)-2-(4-chloro-phenyl)-2-hydroxy-acetylamino]-3-methyl-8-oxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid; triethylamine salt
CAS No.:51465-10-2
Molecular Formula:C₆H₁₅N*C₁₆H₁₅ClN₂O₅S
Molecular Weight:484.016
Hs Code.:

(6<i>R</i>)-7<i>t</i>-[(<i>R</i>)-2-(4-chloro-phenyl)-2-hydroxy-acetylamino]-3-methyl-8-oxo-(6<i>r</i><i>H</i>)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid; triethylamine salt

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Chemical Property of (6R)-7t-[(R)-2-(4-chloro-phenyl)-2-hydroxy-acetylamino]-3-methyl-8-oxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid; triethylamine salt

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Technology Process of (6R)-7t-[(R)-2-(4-chloro-phenyl)-2-hydroxy-acetylamino]-3-methyl-8-oxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid; triethylamine salt

There total 3 articles about (6R)-7t-[(R)-2-(4-chloro-phenyl)-2-hydroxy-acetylamino]-3-methyl-8-oxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid; triethylamine salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 22252-43-3,26395-99-3,70287-30-8,72059-35-9
3-deacetyloxy-7-aminocephalosporanic acid

: 51465-10-2
(6R)-7t-[(R)-2-(4-chloro-phenyl)-2-hydroxy-acetylamino]-3-methyl-8-oxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid; triethylamine salt

Guidance literature:: Multi-step reaction with 2 steps

1: aq. NaHCO₃ / acetone

With sodium hydrogencarbonate; In acetone;
DOI:10.1021/jm00247a008

Reference yield:

: (R)-(4-chloro-phenyl)-dichloroacetoxy-acetyl chloride

: 51465-10-2
(6R)-7t-[(R)-2-(4-chloro-phenyl)-2-hydroxy-acetylamino]-3-methyl-8-oxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid; triethylamine salt

Guidance literature:: Multi-step reaction with 2 steps

1: aq. NaHCO₃ / acetone

With sodium hydrogencarbonate; In acetone;
DOI:10.1021/jm00247a008