Technology Process of (4R,5R)-5-Benzyloxy-2,4-dihydroxy-tetrahydro-pyran-2-carboxylic acid
There total 5 articles about (4R,5R)-5-Benzyloxy-2,4-dihydroxy-tetrahydro-pyran-2-carboxylic acid which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 2.5 g / sodium metaperiodate / H2O / 0.5 h / Ambient temperature
2: 25 percent Chromat. / nickel chloride / H2O; ethanol / 5 h
With
sodium periodate; nickel dichloride;
In
ethanol; water;
DOI:10.1039/P19800001971
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 86 percent / sodium metaperiodate / 1 h / Ambient temperature
2: 90 percent / sodium borohydride / methanol; H2O / 0.5 h / Ambient temperature
3: 2.5 g / sodium metaperiodate / H2O / 0.5 h / Ambient temperature
4: 25 percent Chromat. / nickel chloride / H2O; ethanol / 5 h
With
sodium tetrahydroborate; sodium periodate; nickel dichloride;
In
methanol; ethanol; water;
DOI:10.1039/P19800001971
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1.) sodium hydride / 1.) NN-dimethylformamide, overnight, 2.) Dowex 50 resin (H+), aq. ethanol, 90 deg C, 3 h
2: 86 percent / sodium metaperiodate / 1 h / Ambient temperature
3: 90 percent / sodium borohydride / methanol; H2O / 0.5 h / Ambient temperature
4: 2.5 g / sodium metaperiodate / H2O / 0.5 h / Ambient temperature
5: 25 percent Chromat. / nickel chloride / H2O; ethanol / 5 h
With
sodium tetrahydroborate; sodium periodate; sodium hydride; nickel dichloride;
In
methanol; ethanol; water;
DOI:10.1039/P19800001971
