(S)-5-Diphenylacetyl-6-methoxycarbonyl-1-(4-methoxy-3-methyl-benzyl)-3-(2-oxo-2-phenyl-ethyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridin-1-ium; chloride

Base Information

Chemical Name:(S)-5-Diphenylacetyl-6-methoxycarbonyl-1-(4-methoxy-3-methyl-benzyl)-3-(2-oxo-2-phenyl-ethyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridin-1-ium; chloride
CAS No.:136677-05-9
Molecular Formula:C₃₉H₃₈N₃O₅*Cl
Molecular Weight:664.201
Hs Code.:

(S)-5-Diphenylacetyl-6-methoxycarbonyl-1-(4-methoxy-3-methyl-benzyl)-3-(2-oxo-2-phenyl-ethyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridin-1-ium; chloride

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Chemical Property of (S)-5-Diphenylacetyl-6-methoxycarbonyl-1-(4-methoxy-3-methyl-benzyl)-3-(2-oxo-2-phenyl-ethyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridin-1-ium; chloride

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Technology Process of (S)-5-Diphenylacetyl-6-methoxycarbonyl-1-(4-methoxy-3-methyl-benzyl)-3-(2-oxo-2-phenyl-ethyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridin-1-ium; chloride

There total 3 articles about (S)-5-Diphenylacetyl-6-methoxycarbonyl-1-(4-methoxy-3-methyl-benzyl)-3-(2-oxo-2-phenyl-ethyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridin-1-ium; chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 117-34-0
2,2-diphenylacetic acid

: 136677-05-9
(S)-5-Diphenylacetyl-6-methoxycarbonyl-1-(4-methoxy-3-methyl-benzyl)-3-(2-oxo-2-phenyl-ethyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridin-1-ium; chloride

Guidance literature:: Multi-step reaction with 2 steps

1: dicyclohexylcarbodiimide (DCC), hydroxybenztriazole (HOBT*H₂O) / dimethylformamide

2: 4.76 g / acetonitrile / 2 h / Heating

With benzotriazol-1-ol; dicyclohexyl-carbodiimide; In N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/jm00115a014

Reference yield:

: (S)-3-(2-Oxo-2-phenyl-ethyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-6-carboxylic acid methyl ester

: 136677-05-9
(S)-5-Diphenylacetyl-6-methoxycarbonyl-1-(4-methoxy-3-methyl-benzyl)-3-(2-oxo-2-phenyl-ethyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridin-1-ium; chloride

Guidance literature:: Multi-step reaction with 2 steps

1: dicyclohexylcarbodiimide (DCC), hydroxybenztriazole (HOBT*H₂O) / dimethylformamide

2: 4.76 g / acetonitrile / 2 h / Heating

With benzotriazol-1-ol; dicyclohexyl-carbodiimide; In N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/jm00115a014