Cyclopentanamine, 3-fluoro-, hydrochloride (1:1), (1S,3R)-

Base Information

• Chemical Name: Cyclopentanamine, 3-fluoro-, hydrochloride (1:1), (1S,3R)-
• CAS No.: 932706-21-3
• Molecular Formula: C₅H₁₀FN*ClH
• Molecular Weight: 139.6
• Mol file: 932706-21-3.mol

Synonyms:

Chemical Property of Cyclopentanamine, 3-fluoro-, hydrochloride (1:1), (1S,3R)-

Chemical Property:

Purity/Quality:

98%,99%, ^*data from raw suppliers

cis-3-Fluorocyclopentan-1-amineHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Cyclopentanamine, 3-fluoro-, hydrochloride (1:1), (1S,3R)-

There total 1 articles about Cyclopentanamine, 3-fluoro-, hydrochloride (1:1), (1S,3R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzyl [(1S,3R)-3-fluorocyclopentyl]carbamate (932706-26-8) → (1S, 3R)-3-fluorocyclopentanamine hydrochloride (932706-21-3)

Guidance literature:

benzyl [(1S,3R)-3-fluorocyclopentyl]carbamate; With hydrogen; palladium hydroxide on carbon; In methanol; at 20 ℃; for 20h; under 759.826 Torr;

With hydrogenchloride; In 1,4-dioxane;

Reference yield: 74.0%

(1S, 3R)-3-fluorocyclopentanamine hydrochloride (932706-21-3) + C15H15ClN2O (1187842-53-0) → C20H25ClFN3 (1187842-54-1)

Guidance literature:

With sodium cyanoborohydride; triethylamine; zinc(II) chloride;

DOI:10.1016/j.bmcl.2009.06.095

upstream raw materials:

benzyl [(1S,3R)-3-fluorocyclopentyl]carbamate

Downstream raw materials:

C₂₀H₂₅ClFN₃

Refernces