2-Tert-butyl-2,3,3-trimethylbutanoic acid

Base Information

Chemical Name:2-Tert-butyl-2,3,3-trimethylbutanoic acid
CAS No.:16021-12-8
Molecular Formula:C₁₁H₂₂O₂
Molecular Weight:186.294
Hs Code.:
NSC Number:172553
DSSTox Substance ID:DTXSID70305897
Wikidata:Q82052695
Mol file:16021-12-8.mol

Synonyms:16021-12-8;2-tert-butyl-2,3,3-trimethylbutanoic acid;NSC172553;SCHEMBL847022;DTXSID70305897;NSC-172553;2-tert-butyl-2,3,3-trimethyl-butyric acid

Suppliers and Price of 2-Tert-butyl-2,3,3-trimethylbutanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 2-Tert-butyl-2,3,3-trimethylbutanoic acid

Chemical Property:

Vapor Pressure:0.00257mmHg at 25°C
Boiling Point:266°C at 760 mmHg
Flash Point:116.2°C
Density:0.909g/cm³
XLogP3:3.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:186.161979940
Heavy Atom Count:13
Complexity:189

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)C(C)(C(=O)O)C(C)(C)C

Technology Process of 2-Tert-butyl-2,3,3-trimethylbutanoic acid

There total 6 articles about 2-Tert-butyl-2,3,3-trimethylbutanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 16021-13-9
3,3-Di-tert-butyl-oxetan-2-one

: 16021-12-8
acide trimethyl-2,3,3 t-butyl-2 butyrique

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; for 18h; Heating;
DOI:10.1016/0040-4020(81)85010-7

Reference yield:

: 29571-65-1
2-tert-butyl-3,3-dimethyl-butyryl chloride

: 16021-12-8
acide trimethyl-2,3,3 t-butyl-2 butyrique

Guidance literature:: Multi-step reaction with 3 steps

1: 65 percent / Na / NH₃ / 14 h

2: 69 percent / BF₃-etherate / diethyl ether

3: 70 percent / LiAlH₄ / tetrahydrofuran / 18 h / Heating

With lithium aluminium tetrahydride; boron trifluoride diethyl etherate; sodium; In tetrahydrofuran; diethyl ether; ammonia;
DOI:10.1016/0040-4020(81)85010-7

Reference yield:

: 19824-34-1
di-tert-butylketene

: 16021-12-8
acide trimethyl-2,3,3 t-butyl-2 butyrique

Guidance literature:: Multi-step reaction with 2 steps

1: 69 percent / BF₃-etherate / diethyl ether

2: 70 percent / LiAlH₄ / tetrahydrofuran / 18 h / Heating

With lithium aluminium tetrahydride; boron trifluoride diethyl etherate; In tetrahydrofuran; diethyl ether;
DOI:10.1016/0040-4020(81)85010-7