Technology Process of Nα-benzyloxycarbonyl-Nε-phenylacetyl-L-lysyl-glycine amide
There total 5 articles about Nα-benzyloxycarbonyl-Nε-phenylacetyl-L-lysyl-glycine amide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 6.1 g / 1M-aq. NaOH / 1 h
2: 1) N-ethylpiperidine, 1-hydroxybenzotriazole; 2) dicyclohexylcarbodiimide / 1) DMF; 2) 1 h at -5 deg C, then 16 h at room temp.
With
1-ethyl-piperidine; sodium hydroxide; benzotriazol-1-ol; dicyclohexyl-carbodiimide;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1) copper carbonate dihydroxide; 2) 2M-aq. NaOH ; 3) hydrogen sulfide / 1) water, reflux, 2 h; 2) pH: 10, 30 min; 3) aq. hydrochloric acid (pH: 2), 90 deg C, 1 h
2: 6.1 g / 1M-aq. NaOH / 1 h
3: 1) N-ethylpiperidine, 1-hydroxybenzotriazole; 2) dicyclohexylcarbodiimide / 1) DMF; 2) 1 h at -5 deg C, then 16 h at room temp.
With
1-ethyl-piperidine; sodium hydroxide; copper carbonate dihydroxide; hydrogen sulfide; benzotriazol-1-ol; dicyclohexyl-carbodiimide;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 6.1 g / 1M-aq. NaOH / 1 h
2: 1) N-ethylpiperidine, 1-hydroxybenzotriazole; 2) dicyclohexylcarbodiimide / 1) DMF; 2) 1 h at -5 deg C, then 16 h at room temp.
With
1-ethyl-piperidine; sodium hydroxide; benzotriazol-1-ol; dicyclohexyl-carbodiimide;
