Technology Process of 2-chloromethyl-4-(3,4-dimethoxy-phenyl)-benzo[4,5]thieno[2,3-b]pyridine-3-carboxylic acid ethyl ester
There total 6 articles about 2-chloromethyl-4-(3,4-dimethoxy-phenyl)-benzo[4,5]thieno[2,3-b]pyridine-3-carboxylic acid ethyl ester which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 66 percent / S; morpholine / ethanol / 3 h / Heating
2: 91 percent / pyridine / 2 h / 20 °C
3: 35 percent / 10 percent Pd/C / CHCl3 / 0.17 h / 20 °C
4: 89 percent / 1 N aq. NaOH / ethanol / 5 h / Heating
5: 57 percent / conc. H2SO4; AcOH / 100 °C
With
morpholine; pyridine; sodium hydroxide; palladium on activated charcoal; sulfuric acid; sulfur; acetic acid;
In
ethanol; chloroform;
1: Gewald reaction / 2: Acetylation / 3: Dehydrogenation / 4: Deacetylation / 5: Friedlaender reaction;
DOI:10.1248/cpb.47.993
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 66 percent / S; morpholine / ethanol / 3 h / Heating
2: 91 percent / pyridine / 2 h / 20 °C
3: 35 percent / 10 percent Pd/C / CHCl3 / 0.17 h / 20 °C
4: 89 percent / 1 N aq. NaOH / ethanol / 5 h / Heating
5: 57 percent / conc. H2SO4; AcOH / 100 °C
With
morpholine; pyridine; sodium hydroxide; palladium on activated charcoal; sulfuric acid; sulfur; acetic acid;
In
ethanol; chloroform;
1: Gewald reaction / 2: Acetylation / 3: Dehydrogenation / 4: Deacetylation / 5: Friedlaender reaction;
DOI:10.1248/cpb.47.993