C₁₂H₁₀ClNOS

Base Information

• Chemical Name: C₁₂H₁₀ClNOS
• CAS No.: 1383572-82-4
• Molecular Formula: C₁₂H₁₀ClNOS
• Molecular Weight: 251.737
• Mol file: 1383572-82-4.mol

Synonyms:

Chemical Property of C₁₂H₁₀ClNOS

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₂H₁₀ClNOS

There total 2 articles about C₁₂H₁₀ClNOS which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-chlorothiophene-3-carboxylic acid (53935-71-0) → C12H10ClNOS (1383572-82-4)

Guidance literature:

Multi-step reaction with 2 steps

1: thionyl chloride / Reflux

2: dichloromethane / 0 - 20 °C

With thionyl chloride; In dichloromethane;

DOI:10.1055/s-0031-1289755

Reference yield:

benzylamine (100-46-9) + 2-Chloro-thiophene-3-carbonyl chloride (332370-74-8) → C12H10ClNOS (1383572-82-4)

Guidance literature:

In dichloromethane; at 0 - 20 ℃;

DOI:10.1055/s-0031-1289755

Reference yield:

C12H10ClNOS (1383572-82-4) → N-benzyl-2-hydroxythiophene-3-carboxamide (1383572-75-5)

Guidance literature:

C₁₂H₁₀ClNOS; With copper(l) iodide; 1,10-Phenanthroline; water; at 20 ℃; for 0.166667h;

With potassium hydroxide; at 100 ℃;

DOI:10.1055/s-0031-1289755

upstream raw materials:

2-chlorothiophene-3-carboxylic acid

benzylamine

2-Chloro-thiophene-3-carbonyl chloride

Downstream raw materials:

N-benzyl-2-hydroxythiophene-3-carboxamide