Technology Process of naproxen-L-Phe-L-Phe-L-Tyr phosphate
There total 7 articles about naproxen-L-Phe-L-Phe-L-Tyr phosphate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: sodium carbonate / water; acetone / 12 h / 20 °C
2: dicyclohexyl-carbodiimide / chloroform / 2 h / 20 °C
3: sodium carbonate / water; acetone / 24 h / 20 °C
4: alkaline phosphatase / water / 1 h / pH 7.6 / Enzymatic reaction
With
sodium carbonate; dicyclohexyl-carbodiimide; alkaline phosphatase;
In
chloroform; water; acetone;
DOI:10.3762/bjoc.9.104
- Guidance literature:
-
Multi-step reaction with 3 steps
1: dicyclohexyl-carbodiimide / chloroform / 2 h / 20 °C
2: sodium carbonate / water; acetone / 24 h / 20 °C
3: alkaline phosphatase / water / 1 h / pH 7.6 / Enzymatic reaction
With
sodium carbonate; dicyclohexyl-carbodiimide; alkaline phosphatase;
In
chloroform; water; acetone;
DOI:10.3762/bjoc.9.104
- Guidance literature:
-
Multi-step reaction with 6 steps
1: dicyclohexyl-carbodiimide / chloroform / 2 h / 20 °C
2: sodium carbonate / water; acetone / 12 h / 20 °C
3: sodium carbonate / water; acetone / 12 h / 20 °C
4: dicyclohexyl-carbodiimide / chloroform / 2 h / 20 °C
5: sodium carbonate / water; acetone / 24 h / 20 °C
6: alkaline phosphatase / water / 1 h / pH 7.6 / Enzymatic reaction
With
sodium carbonate; dicyclohexyl-carbodiimide; alkaline phosphatase;
In
chloroform; water; acetone;
DOI:10.3762/bjoc.9.104