C₂₂H₁₈BrNO₆S

Base Information

• Chemical Name: C₂₂H₁₈BrNO₆S
• CAS No.: 1446308-72-0
• Molecular Formula: C₂₂H₁₈BrNO₆S
• Molecular Weight: 504.358
• Mol file: 1446308-72-0.mol

Synonyms:

Chemical Property of C₂₂H₁₈BrNO₆S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₂H₁₈BrNO₆S

There total 4 articles about C₂₂H₁₈BrNO₆S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

p-toluenesulfonyl chloride (98-59-9) → C22H18BrNO6S (1446308-72-0)

Guidance literature:

Multi-step reaction with 4 steps

1: lithium borohydride

2: methanesulfonyl chloride

3: potassium carbonate

4: zinc trifluoromethanesulfonate / toluene / 1 h / 120 °C / Microwave irradiation

With lithium borohydride; zinc trifluoromethanesulfonate; potassium carbonate; methanesulfonyl chloride; In toluene; 4: |Claisen Rearrangement;

DOI:10.1016/j.tetlet.2013.05.002

Reference yield:

C16H13BrClNO2S (1446308-70-8) → C22H18BrNO6S (1446308-72-0)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate

2: zinc trifluoromethanesulfonate / toluene / 1 h / 120 °C / Microwave irradiation

With zinc trifluoromethanesulfonate; potassium carbonate; In toluene; 2: |Claisen Rearrangement;

DOI:10.1016/j.tetlet.2013.05.002

Reference yield:

4-bromo-1H-indole-2-carboxylic acid methyl ester (167479-13-2) → C22H18BrNO6S (1446308-72-0)

Guidance literature:

Multi-step reaction with 4 steps

1: lithium borohydride

2: methanesulfonyl chloride

3: potassium carbonate

4: zinc trifluoromethanesulfonate / toluene / 1 h / 120 °C / Microwave irradiation

With lithium borohydride; zinc trifluoromethanesulfonate; potassium carbonate; methanesulfonyl chloride; In toluene; 4: |Claisen Rearrangement;

DOI:10.1016/j.tetlet.2013.05.002

upstream raw materials:

4-bromo-1H-indole-2-carboxylic acid methyl ester

C₁₆H₁₄BrNO₃S

p-toluenesulfonyl chloride

C₁₆H₁₃BrClNO₂S