N,N'-bis(4-hydroxyphenyl)-2,2'-thiodibenzamide

Base Information

• Chemical Name: N,N'-bis(4-hydroxyphenyl)-2,2'-thiodibenzamide
• CAS No.: 1393085-68-1
• Molecular Formula: C₂₆H₂₀N₂O₄S
• Molecular Weight: 456.522
• Mol file: 1393085-68-1.mol

Synonyms:

Chemical Property of N,N'-bis(4-hydroxyphenyl)-2,2'-thiodibenzamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N,N'-bis(4-hydroxyphenyl)-2,2'-thiodibenzamide

There total 2 articles about N,N'-bis(4-hydroxyphenyl)-2,2'-thiodibenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

2,2'-thiodibenzoic acid (22219-02-9) + 4-amino-phenol (123-30-8) → N,N'-bis(4-hydroxyphenyl)-2,2'-thiodibenzamide (1393085-68-1)

Guidance literature:

2,2'-thiodibenzoic acid; With thionyl chloride; In dichloromethane; for 2h; Reflux;

4-amino-phenol;

DOI:10.1080/10426507.2012.685996

Reference yield:

ortho-chlorobenzoic acid (118-91-2) → N,N'-bis(4-hydroxyphenyl)-2,2'-thiodibenzamide (1393085-68-1)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 20 °C

1.2: 5 h / Reflux; Inert atmosphere

2.1: thionyl chloride / dichloromethane / 2 h / Reflux

With thionyl chloride; sodium hydride; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1080/10426507.2012.685996

upstream raw materials:

2,2'-thiodibenzoic acid

4-amino-phenol

ortho-chlorobenzoic acid

Refernces