(1aR^*,4aR^*,5R^*,7aR^*,7bS^*)-decahydro-3,3,5,7b-tetramethyl-4aH-cyclopropazulen-4a-ol

Base Information

• Chemical Name: (1aR^*,4aR^*,5R^*,7aR^*,7bS^*)-decahydro-3,3,5,7b-tetramethyl-4aH-cyclopropazulen-4a-ol
• CAS No.: 132077-05-5
• Molecular Formula: C₁₅H₂₆O
• Molecular Weight: 222.371
• Mol file: 132077-05-5.mol

Synonyms:

Chemical Property of (1aR^*,4aR^*,5R^*,7aR^*,7bS^*)-decahydro-3,3,5,7b-tetramethyl-4aH-cyclopropazulen-4a-ol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1aR^*,4aR^*,5R^*,7aR^*,7bS^*)-decahydro-3,3,5,7b-tetramethyl-4aH-cyclopropazulen-4a-ol

There total 55 articles about (1aR^*,4aR^*,5R^*,7aR^*,7bS^*)-decahydro-3,3,5,7b-tetramethyl-4aH-cyclopropazulen-4a-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

(1aS,4aS,7aS,7bR)-3,3,7b-Trimethyl-5-methylene-decahydro-cyclopropa[e]azulen-4a-ol (78173-24-7) → (+/-)-Africanol (53823-07-7,74923-35-6,104975-19-1,107869-99-8,132077-05-5,132077-06-6,149341-35-5)

Guidance literature:

With hydrogen; platinum(IV) oxide; In ethyl acetate; at 0 ℃;

DOI:10.1016/0040-4039(80)80152-3

Reference yield: 90.0%

(1aR*,4aS*,7aR*,7bS*)-1,1a,2,3,4,7,7a,7b-octahydro-3,3,5,7b-tetramethyl-4aH-cyclopropazulen-4a-ol (107770-67-2,107869-98-7) → (1aR*,4aR*,5R*,7aR*,7bS*)-decahydro-3,3,5,7b-tetramethyl-4aH-cyclopropazulen-4a-ol (53823-07-7,74923-35-6,104975-19-1,107869-99-8,132077-05-5,132077-06-6,149341-35-5)

Guidance literature:

With hydrogen; platinum(IV) oxide; In ethyl acetate; for 24h; under 2585.7 Torr;

DOI:10.1021/ja00244a026

Reference yield: 88.0%

(1aR*,4aR*,7aR*,7bS*)-1,1a,2,3,4,7,7a,7b-octahydro-3,3,5,7b-tetramethyl-4aH-cyclopropazulen-4a-ol (107770-67-2,107869-98-7) → (+/-)-Africanol (53823-07-7,74923-35-6,104975-19-1,107869-99-8,132077-05-5,132077-06-6,149341-35-5)

Guidance literature:

With hydrogen; platinum(IV) oxide; In ethyl acetate; for 72h; under 2585.7 Torr;

DOI:10.1021/ja00244a026

upstream raw materials:

(1S,2S,8S)-2-(4'-butenyl)-1,5,5-trimethyl-bicyclo<5.1.0>-3-octanone

diiodomethane

(1aS,4aS,7aS,7bR)-3,3,7b-Trimethyl-5-methylene-decahydro-cyclopropa[e]azulen-4a-ol

(1aR^*,4aR^*,7aR^*,7bS^*)-1,1a,2,3,4,7,7a,7b-octahydro-3,3,5,7b-tetramethyl-4aH-cyclopropazulen-4a-ol