N-Aethyl-1-phenyl-1-methyl-propargylamin

Base Information

• Chemical Name: N-Aethyl-1-phenyl-1-methyl-propargylamin
• CAS No.: 805180-83-0
• Molecular Formula: C₁₂H₁₅N
• Molecular Weight: 173.258
• Mol file: 805180-83-0.mol

Synonyms:

Chemical Property of N-Aethyl-1-phenyl-1-methyl-propargylamin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-Aethyl-1-phenyl-1-methyl-propargylamin

There total 2 articles about N-Aethyl-1-phenyl-1-methyl-propargylamin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-Chlor-3-aethylamino-3-phenyl-but-1-en → N-Aethyl-1-phenyl-1-methyl-propargylamin (805180-83-0)

Guidance literature:

With sodium amide; In ammonia;

DOI:10.1021/jo01055a010

Reference yield:

2-Phenyl-3-butyn-2-ol (127-66-2) → N-Aethyl-1-phenyl-1-methyl-propargylamin (805180-83-0)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) HCl, (ii) /BRN= 505933/

2: NaNH₂ / liquid ammonia

With sodium amide; In ammonia;

DOI:10.1021/jo01055a010

Reference yield:

N-Aethyl-1-phenyl-1-methyl-propargylamin (805180-83-0) → Aethyl-<2-(1-methyl-3-phenyl-butoxy)-aethyl>-amin (5933-17-5)

Guidance literature:

Multi-step reaction with 4 steps

1: (i) NaNH₂, liq. NH₃, Et₂O, (ii) /BRN= 969135/

3: KOH / xylene / 4 h / Heating

4: H₂ / Pd-C / ethanol

With potassium hydroxide; hydrogen; palladium on activated charcoal; In ethanol; xylene;

DOI:10.1021/jo01339a026

upstream raw materials:

2-Phenyl-3-butyn-2-ol

Downstream raw materials:

3-amino-3-phenyl-but-1-in

<1--1-methyl-propin-(2)-yl>-benzol

1-ethyl-3-methyl-1-(1-methyl-1-phenyl-prop-2-ynyl)-urea

Aethyl-<1-methyl-1-phenyl-but-2-inyl>-amin