1-benzyl-4-(1H-pyrazol-3-yl)-piperidine

Base Information

Chemical Name:1-benzyl-4-(1H-pyrazol-3-yl)-piperidine
CAS No.:690262-01-2
Molecular Formula:C₁₅H₁₉N₃
Molecular Weight:241.336
Hs Code.:

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Chemical Property of 1-benzyl-4-(1H-pyrazol-3-yl)-piperidine

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Technology Process of 1-benzyl-4-(1H-pyrazol-3-yl)-piperidine

There total 5 articles about 1-benzyl-4-(1H-pyrazol-3-yl)-piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1122-54-9
methyl (4-pyridyl) ketone

: 690262-01-2
1-benzyl-4-(1H-pyrazol-3-yl)-piperidine

Guidance literature:: Multi-step reaction with 5 steps

1: sodium methylate / benzene / 18 h / Heating / reflux

2: hydrazine dihydrochloride / water / 2 h / 20 °C

3: isopropyl alcohol / 0.17 h / 80 °C / Heating / reflux

4: sodium tetrahydroborate / ethanol / 1 h / 0 °C

5: hydrogen / palladium 10% on activated carbon / 16 h / 2068.65 Torr

With sodium tetrahydroborate; hydrazine dihydrochloride; hydrogen; sodium methylate; palladium 10% on activated carbon; In ethanol; water; isopropyl alcohol; benzene;

Reference yield:

: C₁₀H₁₃NO₃

: 690262-01-2
1-benzyl-4-(1H-pyrazol-3-yl)-piperidine

Guidance literature:: Multi-step reaction with 4 steps

1: hydrazine dihydrochloride / water / 2 h / 20 °C

2: isopropyl alcohol / 0.17 h / 80 °C / Heating / reflux

3: sodium tetrahydroborate / ethanol / 1 h / 0 °C

4: hydrogen / palladium 10% on activated carbon / 16 h / 2068.65 Torr

With sodium tetrahydroborate; hydrazine dihydrochloride; hydrogen; palladium 10% on activated carbon; In ethanol; water; isopropyl alcohol;

Reference yield:

: C₁₅H₁₅N₃

: 690262-01-2
1-benzyl-4-(1H-pyrazol-3-yl)-piperidine

Guidance literature:: Multi-step reaction with 2 steps

1: sodium tetrahydroborate / ethanol / 1 h / 0 °C

2: hydrogen / palladium 10% on activated carbon / 16 h / 2068.65 Torr

With sodium tetrahydroborate; hydrogen; palladium 10% on activated carbon; In ethanol;