(+/-)-galanolactone

Base Information

Chemical Name:(+/-)-galanolactone
CAS No.:123619-18-1
Molecular Formula:C₂₀H₃₀O₃
Molecular Weight:318.456
Hs Code.:

Synonyms:

Suppliers and Price of (+/-)-galanolactone

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (+/-)-galanolactone

Chemical Property:

Purity/Quality:

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Technology Process of (+/-)-galanolactone

There total 18 articles about (+/-)-galanolactone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3-(diethylphosphonio)tetrahydrofuran-2-one

: 123522-42-9
C₁₆H₂₆O₂

: 115753-79-2,123619-18-1,123619-23-8
C₂₀H₃₀O₃

: 115753-79-2,123619-18-1,123619-23-8
(+/-)-galanolactone

Guidance literature:: With sodium hydride; In toluene; at 0 - 80 ℃; for 1h; Yield given. Yields of byproduct given;
DOI:10.1016/S0040-4039(00)95251-1

Reference yield:

: 3-(diethylphosphonio)tetrahydrofuran-2-one

: 123522-42-9
C₁₆H₂₆O₂

: 115753-79-2,123619-18-1,123619-23-8
C₂₀H₃₀O₃

: 115753-79-2,123619-18-1,123619-23-8
(+/-)-galanolactone

Guidance literature:: With sodium hydride; In toluene; at 0 - 80 ℃; for 1h; Yield given. Yields of byproduct given;
DOI:10.1016/S0040-4039(00)95251-1

Reference yield:

: 87957-15-1,91547-83-0,124578-47-8
8-keto-9β-cyanomethyl-(4α,4β),10β-trimethyl-(trans)-decahydronaphthalene

: 115753-79-2,123619-18-1,123619-23-8
C₂₀H₃₀O₃

Guidance literature:: Multi-step reaction with 9 steps

1: TMS-triflate / CH₂Cl₂ / 0 °C

2: 80 percent / diisobutylaluminium hydride / toluene / 0.5 h / 0 °C

3: 100 percent / NaBH₄ / ethanol / 1 h / Ambient temperature

4: 0.1 N HCl / acetone / Ambient temperature

5: imidazole / tetrahydrofuran / Ambient temperature

6: t-BuOK / tetrahydrofuran; dimethylsulfoxide / 0 deg C, 30 min, then r.t., 1 h

7: Bu₄NF / tetrahydrofuran / 3 h / Ambient temperature

8: 1) (COCl)2, 2) Et₃N / dimethylsulfoxide / 1) 60 deg C, 10 min, 2) 15 min

9: NaH / toluene / 1 h / 0 - 80 °C

With 1H-imidazole; hydrogenchloride; sodium tetrahydroborate; oxalyl dichloride; trimethylsilyl trifluoromethanesulfonate; potassium tert-butylate; tetrabutyl ammonium fluoride; sodium hydride; diisobutylaluminium hydride; triethylamine; In tetrahydrofuran; ethanol; dichloromethane; dimethyl sulfoxide; acetone; toluene;
DOI:10.1016/S0040-4039(00)95251-1