2-Chloro-5-cyanopyridine

Base Information Edit

Chemical Name:2-Chloro-5-cyanopyridine
CAS No.:33252-28-7
Molecular Formula:C6H3ClN2
Molecular Weight:138.556
Hs Code.:29333990
DSSTox Substance ID:DTXSID80408888
Nikkaji Number:J357.443A
Wikidata:Q72455633
Mol file:33252-28-7.mol

Synonyms:2-Chloro-5-cyanopyridine;33252-28-7;6-Chloronicotinonitrile;6-chloropyridine-3-carbonitrile;6-Chloro-3-pyridinecarbonitrile;6-chloro-nicotinonitrile;2-CHLORO-5-PYRIDINECARBONITRILE;2-Chloropyridine-5-carbonitrile;6-chloro nicotinonitrile;6-Chloro-3-cyanopyridine;MFCD00084941;3-PYRIDINECARBONITRILE, 6-CHLORO-;2-chloro-5-cyano pyridine;2-chloro-5-cyano-pyridine;6-Chloronicotinitrile;6-chloronicotino-nitrile;6-chloro-nicotino-nitrile;2-Chloro,5-cyanopyridine;5-Cyano-2-chloropyridine;2-chloro -5-cyanopyridine;2-chloro- 5-cyanopyridine;2-chloro-5-(cyano)pyridine;SCHEMBL75830;2-chloro -5-(cyano)pyridine;2-Chloro pyridine-5-carbonitrile;2-chloro-pyridine-5-carbonitrile;6-chloro-3-pyridine carbonitrile;6-chloro-3-pyridine-carbonitrile;DTXSID80408888;ORIQLMBUPMABDV-UHFFFAOYSA-N;BCP11416;CL0236;AKOS000121128;6-Chloro-3-pyridinecarbonitrile, 97%;AB03166;AC-2475;CS-W020115;SB11104;BP-21215;HY-59197;SY001536;AM20051078;C2056;FT-0621083;NS00124151;EN300-25566;A15490;A18645;11X-0845;J-400295;Q-101239;F0001-0983

Suppliers and Price of 2-Chloro-5-cyanopyridine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Chloro-5-cyanopyridine
5g
$ 140.00

TCI Chemical
2-Chloro-5-cyanopyridine >97.0%(GC)(N)
5g
$ 38.00

TCI Chemical
2-Chloro-5-cyanopyridine >97.0%(GC)(N)
25g
$ 142.00

SynQuest Laboratories
6-Chloronicotinonitrile
100 g
$ 167.00

SynQuest Laboratories
6-Chloronicotinonitrile
25 g
$ 61.00

SynQuest Laboratories
6-Chloronicotinonitrile
5 g
$ 16.00

SynChem
2-Chloro-5-Cyanopyridine 95+%
1 g
$ 20.00

SynChem
2-Chloro-5-Cyanopyridine 95+%
5 g
$ 38.00

Sigma-Aldrich
6-Chloro-3-pyridinecarbonitrile 97%
25g
$ 73.10

Sigma-Aldrich
6-Chloro-3-pyridinecarbonitrile 97%
5g
$ 51.40

Total 187 raw suppliers

Chemical Property of 2-Chloro-5-cyanopyridine Edit

Chemical Property:

Appearance/Colour:Yellow to brown crystal
Vapor Pressure:0.0474mmHg at 25°C
Melting Point:113-116 °C
Refractive Index:1.565
Boiling Point:236.4 °C at 760 mmHg
PKA:-3.56±0.10(Predicted)
Flash Point:96.8 °C
PSA：36.68000
Density:1.33 g/cm³
LogP:1.60668
Storage Temp.:Keep in dark place,Sealed in dry,Room Temperature
Solubility.:Ethanol
XLogP3:1.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:137.9984758
Heavy Atom Count:9
Complexity:137

Purity/Quality:

99% ^*data from raw suppliers

2-Chloro-5-cyanopyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn,T,Xi
Hazard Codes:Xn,T,Xi
Statements: 20/21/22-36/37/38
Safety Statements: 26-36-36/37/39-37

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=CC(=NC=C1C#N)Cl
Uses 2-Chloro-5-cyanopyridine (cas# 33252-28-7) is a compound useful in organic synthesis. 6-Chloro-3-pyridinecarbonitrile (2-Chloro-5-cyanopyridine) may be used in the preparation of:(6-chloro-3-pyridyl)methylamine2-(N-methyl-N-isopropylamino)-5-cyanopyridineS-(5-cyano-2-pyridyl)thiouronium chloride

Technology Process of 2-Chloro-5-cyanopyridine

There total 20 articles about 2-Chloro-5-cyanopyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 23100-12-1
6-chloronicotinylaldehyde

: 33252-28-7
6-chloronicotinonitrile

Guidance literature:: With hydroxylamine hydrochloride; 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; triethylamine; In ethyl acetate; N,N-dimethyl-formamide; at 100 ℃;
DOI:10.1055/s-0029-1218388