(S)-2-[(S)-2-(2-Benzyloxycarbonylamino-acetylamino)-propionylamino]-3-phenyl-thiopropionic acid S-[2-(2-{(2S,3S)-3-[2-(2-mercapto-ethoxy)-ethoxymethyl]-1,4,7,10,13,16-hexaoxa-cyclooctadec-2-ylmethoxy}-ethoxy)-ethyl] ester

Base Information

Chemical Name:(S)-2-[(S)-2-(2-Benzyloxycarbonylamino-acetylamino)-propionylamino]-3-phenyl-thiopropionic acid S-[2-(2-{(2S,3S)-3-[2-(2-mercapto-ethoxy)-ethoxymethyl]-1,4,7,10,13,16-hexaoxa-cyclooctadec-2-ylmethoxy}-ethoxy)-ethyl] ester
CAS No.:118404-30-1
Molecular Formula:C₄₄H₆₇N₃O₁₅S₂
Molecular Weight:942.159
Hs Code.:

(S)-2-[(S)-2-(2-Benzyloxycarbonylamino-acetylamino)-propionylamino]-3-phenyl-thiopropionic acid S-[2-(2-{(2S,3S)-3-[2-(2-mercapto-ethoxy)-ethoxymethyl]-1,4,7,10,13,16-hexaoxa-cyclooctadec-2-ylmethoxy}-ethoxy)-ethyl] ester

Synonyms:

Suppliers and Price of (S)-2-[(S)-2-(2-Benzyloxycarbonylamino-acetylamino)-propionylamino]-3-phenyl-thiopropionic acid S-[2-(2-{(2S,3S)-3-[2-(2-mercapto-ethoxy)-ethoxymethyl]-1,4,7,10,13,16-hexaoxa-cyclooctadec-2-ylmethoxy}-ethoxy)-ethyl] ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-2-[(S)-2-(2-Benzyloxycarbonylamino-acetylamino)-propionylamino]-3-phenyl-thiopropionic acid S-[2-(2-{(2S,3S)-3-[2-(2-mercapto-ethoxy)-ethoxymethyl]-1,4,7,10,13,16-hexaoxa-cyclooctadec-2-ylmethoxy}-ethoxy)-ethyl] ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-2-[(S)-2-(2-Benzyloxycarbonylamino-acetylamino)-propionylamino]-3-phenyl-thiopropionic acid S-[2-(2-{(2S,3S)-3-[2-(2-mercapto-ethoxy)-ethoxymethyl]-1,4,7,10,13,16-hexaoxa-cyclooctadec-2-ylmethoxy}-ethoxy)-ethyl] ester

There total 8 articles about (S)-2-[(S)-2-(2-Benzyloxycarbonylamino-acetylamino)-propionylamino]-3-phenyl-thiopropionic acid S-[2-(2-{(2S,3S)-3-[2-(2-mercapto-ethoxy)-ethoxymethyl]-1,4,7,10,13,16-hexaoxa-cyclooctadec-2-ylmethoxy}-ethoxy)-ethyl] ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₄₄H₆₇N₃O₁₅S₂*ClH

: 118404-30-1
(S)-2-[(S)-2-(2-Benzyloxycarbonylamino-acetylamino)-propionylamino]-3-phenyl-thiopropionic acid S-[2-(2-{(2S,3S)-3-[2-(2-mercapto-ethoxy)-ethoxymethyl]-1,4,7,10,13,16-hexaoxa-cyclooctadec-2-ylmethoxy}-ethoxy)-ethyl] ester

Guidance literature:: With TEA; Trimethylacetic acid; In benzene; for 48h; Yield given; Ambient temperature;
DOI:10.1248/cpb.37.912

Reference yield:

: 68394-45-6
(2S,3S)-2,3-Bis(hydroxymethyl)-1,4,7,10,13,16-hexaoxacyclooctadecan

: 118404-30-1
(S)-2-[(S)-2-(2-Benzyloxycarbonylamino-acetylamino)-propionylamino]-3-phenyl-thiopropionic acid S-[2-(2-{(2S,3S)-3-[2-(2-mercapto-ethoxy)-ethoxymethyl]-1,4,7,10,13,16-hexaoxa-cyclooctadec-2-ylmethoxy}-ethoxy)-ethyl] ester

Guidance literature:: Multi-step reaction with 7 steps

1: 1.) NaH(50 percent in oil) / 1.) DMF, 1 h, room t., then 40 deg C, 1 h, 2.) DMF, room t., 17 h

2: ethanol / 1 h / Heating

3: 5 N NaOH / ethanol / 1 h / 40 °C

4: 1.) Et₃N, diethyl pyrocarbonate 2.) pyridine / 1.) DMF, 0 deg C, 1 h, then room t., 1 h, 2.) room t., 20 min

5: 81 percent / pivalic acid, TEA / benzene / 10 h / Ambient temperature

6: pyridine / Ambient temperature

7: t-BuCOOH, TEA / benzene / 48 h / Ambient temperature

With pyridine; sodium hydroxide; TEA; sodium hydride; triethylamine; diethyl dicarbonate; Trimethylacetic acid; In ethanol; benzene;
DOI:10.1248/cpb.37.912

Reference yield:

: 17663-35-3
L-phenylalanine p-nitrophenyl ester

: 118404-30-1
(S)-2-[(S)-2-(2-Benzyloxycarbonylamino-acetylamino)-propionylamino]-3-phenyl-thiopropionic acid S-[2-(2-{(2S,3S)-3-[2-(2-mercapto-ethoxy)-ethoxymethyl]-1,4,7,10,13,16-hexaoxa-cyclooctadec-2-ylmethoxy}-ethoxy)-ethyl] ester

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / Ambient temperature

2: t-BuCOOH, TEA / benzene / 48 h / Ambient temperature

With pyridine; TEA; Trimethylacetic acid; In benzene;
DOI:10.1248/cpb.37.912