(E)-3-Benzylamino-2-((E)-2-benzylamino-1-{2-[(E)-benzylimino]-ethylcarbamoyl}-ethenesulfonyl)-N-{2-[(Z)-benzylimino]-ethyl}-acrylamide

Base Information

• Chemical Name: (E)-3-Benzylamino-2-((E)-2-benzylamino-1-{2-[(E)-benzylimino]-ethylcarbamoyl}-ethenesulfonyl)-N-{2-[(Z)-benzylimino]-ethyl}-acrylamide
• CAS No.: 143970-80-3
• Molecular Formula: C₃₈H₄₀N₆O₄S
• Molecular Weight: 676.839
• Mol file: 143970-80-3.mol

Synonyms:

Chemical Property of (E)-3-Benzylamino-2-((E)-2-benzylamino-1-{2-[(E)-benzylimino]-ethylcarbamoyl}-ethenesulfonyl)-N-{2-[(Z)-benzylimino]-ethyl}-acrylamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-3-Benzylamino-2-((E)-2-benzylamino-1-{2-[(E)-benzylimino]-ethylcarbamoyl}-ethenesulfonyl)-N-{2-[(Z)-benzylimino]-ethyl}-acrylamide

There total 9 articles about (E)-3-Benzylamino-2-((E)-2-benzylamino-1-{2-[(E)-benzylimino]-ethylcarbamoyl}-ethenesulfonyl)-N-{2-[(Z)-benzylimino]-ethyl}-acrylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,2'-sulfonylbis (132417-38-0) → (E)-3-Benzylamino-2-((E)-2-benzylamino-1-{2-[(E)-benzylimino]-ethylcarbamoyl}-ethenesulfonyl)-N-{2-[(Z)-benzylimino]-ethyl}-acrylamide (143970-80-3)

Guidance literature:

Multi-step reaction with 4 steps

1: 91 percent / acetonitrile / 31 h / Ambient temperature

2: 96 percent / acetonitrile / 3 h / Ambient temperature

3: 74 percent / I₂, hexamethyldisilane / CH₂Cl₂ / 3 h / Ambient temperature

4: molecular sieves (3A) / acetonitrile / 18 h

With 1,1,1,2,2,2-hexamethyldisilane; 3 A molecular sieve; iodine; In dichloromethane; acetonitrile;

DOI:10.1021/jo00048a019

Reference yield:

2,2'-sulfonylbis<3-(dimethylamino)-(E,E)-2-(N-(2,2-dimethoxyethyl))propenamide> (132417-43-7) → (E)-3-Benzylamino-2-((E)-2-benzylamino-1-{2-[(E)-benzylimino]-ethylcarbamoyl}-ethenesulfonyl)-N-{2-[(Z)-benzylimino]-ethyl}-acrylamide (143970-80-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 96 percent / acetonitrile / 3 h / Ambient temperature

2: 74 percent / I₂, hexamethyldisilane / CH₂Cl₂ / 3 h / Ambient temperature

3: molecular sieves (3A) / acetonitrile / 18 h

With 1,1,1,2,2,2-hexamethyldisilane; 3 A molecular sieve; iodine; In dichloromethane; acetonitrile;

DOI:10.1021/jo00048a019

Reference yield:

2,2'-sulfonylbis<3-(benzylamino)-(E,E)-2-(N-(2,2-dimethoxyethyl))-propenamide> (132417-49-3) → (E)-3-Benzylamino-2-((E)-2-benzylamino-1-{2-[(E)-benzylimino]-ethylcarbamoyl}-ethenesulfonyl)-N-{2-[(Z)-benzylimino]-ethyl}-acrylamide (143970-80-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 74 percent / I₂, hexamethyldisilane / CH₂Cl₂ / 3 h / Ambient temperature

2: molecular sieves (3A) / acetonitrile / 18 h

With 1,1,1,2,2,2-hexamethyldisilane; 3 A molecular sieve; iodine; In dichloromethane; acetonitrile;

DOI:10.1021/jo00048a019

upstream raw materials:

2,2'-sulfonylbis<3-(benzylamino)-(E,E)-N-(2-oxoethyl)propenamide>

benzylamine

2,2'-sulfonylbis

2,2'-sulfonylbis<3-(dimethylamino)-(E,E)-2-(N-(2,2-dimethoxyethyl))propenamide>